Literature DB >> 1920639

Induction of alpha interferon by human immunodeficiency virus type 1 in human monocyte-macrophage cultures.

J Szebeni1, C Dieffenbach, S M Wahl, C N Venkateshan, A Yeh, M Popovic, S Gartner, L M Wahl, M Peterfy, R M Friedman.   

Abstract

The induction of interferon (IFN) by human immunodeficiency virus type 1 (HIV-1) in primary, nonstimulated monocyte-macrophage cultures was studied. HIV-1 infection, as confirmed by p24 antigen levels in the cell supernatant, led to the production of alpha interferon (IFN-alpha) over 7 to 21 days following infection. In two of seven experiments, the IFN detected was acid labile. Coupled reverse transcription-polymerase chain reaction analysis confirmed the induction of IFN-alpha mRNA in cells of HIV-1-infected cultures.

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Year:  1991        PMID： 1920639      PMCID： PMC250359     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  23 in total

1.  Regulation of interferon production by human monocytes: requirements for priming for lipopolysaccharide-induced production.

Authors:  M P Hayes; J C Enterline; T L Gerrard; K C Zoon
Journal:  J Leukoc Biol       Date:  1991-08       Impact factor: 4.962

2.  Interleukin-1 and tumor necrosis factor alpha can be induced from mononuclear phagocytes by human immunodeficiency virus type 1 binding to the CD4 receptor.

Authors:  J E Merrill; Y Koyanagi; I S Chen
Journal:  J Virol       Date:  1989-10       Impact factor: 5.103

3.  Isolation of human mononuclear cell subsets by counterflow centrifugal elutriation (CCE). I. Characterization of B-lymphocyte-, T-lymphocyte-, and monocyte-enriched fractions by flow cytometric analysis.

Authors:  L M Wahl; I M Katona; R L Wilder; C C Winter; B Haraoui; I Scher; S M Wahl
Journal:  Cell Immunol       Date:  1984-05       Impact factor: 4.868

4.  Acid-labile human leukocyte interferon in homosexual men with Kaposi's sarcoma and lymphadenopathy.

Authors:  E DeStefano; R M Friedman; A E Friedman-Kien; J J Goedert; D Henriksen; O T Preble; J A Sonnabend; J Vilcek
Journal:  J Infect Dis       Date:  1982-10       Impact factor: 5.226

5.  Enhanced HIV replication in macrophage colony-stimulating factor-treated monocytes.

Authors:  D C Kalter; M Nakamura; J A Turpin; L M Baca; D L Hoover; C Dieffenbach; P Ralph; H E Gendelman; M S Meltzer
Journal:  J Immunol       Date:  1991-01-01       Impact factor: 5.422

6.  Acid-labile alpha interferon. A possible preclinical marker for the acquired immunodeficiency syndrome in hemophilia.

Authors:  M E Eyster; J J Goedert; M C Poon; O T Preble
Journal:  N Engl J Med       Date:  1983-09-08       Impact factor: 91.245

7.  Automated, quantitative cytopathic effect reduction assay for interferon.

Authors:  T J Yeh; P T McBride; J C Overall; J A Green
Journal:  J Clin Microbiol       Date:  1982-08       Impact factor: 5.948

8.  Detection of high levels of immunoreactive human beta-1 interferon in sera from HIV-infected patients.

Authors:  T Minagawa; K Mizuno; S Hirano; M Asano; A Numata; M Kohanawa; A Nakane; K Hachimori; S Tamagawa; M Negishi
Journal:  Life Sci       Date:  1989       Impact factor: 5.037

9.  A selective defect of interferon alpha production in human immunodeficiency virus-infected monocytes.

Authors:  H E Gendelman; R M Friedman; S Joe; L M Baca; J A Turpin; G Dveksler; M S Meltzer; C Dieffenbach
Journal:  J Exp Med       Date:  1990-11-01       Impact factor: 14.307

10.  Macrophage- and astrocyte-derived transforming growth factor beta as a mediator of central nervous system dysfunction in acquired immune deficiency syndrome.

Authors:  S M Wahl; J B Allen; N McCartney-Francis; M C Morganti-Kossmann; T Kossmann; L Ellingsworth; U E Mai; S E Mergenhagen; J M Orenstein
Journal:  J Exp Med       Date:  1991-04-01       Impact factor: 14.307
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  19 in total

1.  Structural variants of IFNα preferentially promote antiviral functions.

Authors:  Nancy Vázquez; Hana Schmeisser; Michael A Dolan; Joseph Bekisz; Kathryn C Zoon; Sharon M Wahl
Journal:  Blood       Date:  2011-07-14       Impact factor: 22.113

2.  Human X-DING-CD4 mediates resistance to HIV-1 infection through novel paracrine-like signaling.

Authors:  Rakhee Sachdeva; Yuchang Li; Rasheda Y Shilpi; Malgorzata Simm
Journal:  FEBS J       Date:  2015-01-27       Impact factor: 5.542

3.  In vitro treatment of human monocytes/macrophages with myristoylated recombinant Nef of human immunodeficiency virus type 1 leads to the activation of mitogen-activated protein kinases, IkappaB kinases, and interferon regulatory factor 3 and to the release of beta interferon.

Authors:  Giorgio Mangino; Zulema A Percario; Gianna Fiorucci; Gabriele Vaccari; Santiago Manrique; Giovanna Romeo; Maurizio Federico; Matthias Geyer; Elisabetta Affabris
Journal:  J Virol       Date:  2006-12-20       Impact factor: 5.103

4.  HIV-1 envelope glycoprotein gp120 down-regulates CD4 expression in primary human macrophages through induction of endogenous tumour necrosis factor-alpha.

Authors:  V Karsten; S Gordon; A Kirn; G Herbein
Journal:  Immunology       Date:  1996-05       Impact factor: 7.397

5.  Induction of beta interferon by human immunodeficiency virus type 1 and its gp120 protein in human monocytes-macrophages: role of beta interferon in restriction of virus replication.

Authors:  S Gessani; P Puddu; B Varano; P Borghi; L Conti; L Fantuzzi; F Belardelli
Journal:  J Virol       Date:  1994-03       Impact factor: 5.103

6.  Immunocytochemical localization of the endogenous neuroexcitotoxin quinolinate in human peripheral blood monocytes/macrophages and the effect of human T-cell lymphotropic virus type I infection.

Authors:  C N Venkateshan; R Narayanan; M G Espey; J R Moffett; D C Gajdusek; C J Gibbs; M A Namboodiri
Journal:  Proc Natl Acad Sci U S A       Date:  1996-02-20       Impact factor: 11.205

7.  Effects of the tat and nef gene products of human immunodeficiency virus type 1 (HIV-1) on transcription controlled by the HIV-1 long terminal repeat and on cell growth in macrophages.

Authors:  K M Murphy; M J Sweet; I L Ross; D A Hume
Journal:  J Virol       Date:  1993-12       Impact factor: 5.103

8.  Tetherin/BST-2 is essential for the formation of the intracellular virus-containing compartment in HIV-infected macrophages.

Authors:  Hin Chu; Jaang-Jiun Wang; Mingli Qi; Jeong-Joong Yoon; Xuemin Chen; Xiaoyun Wen; Jason Hammonds; Lingmei Ding; Paul Spearman
Journal:  Cell Host Microbe       Date:  2012-09-13       Impact factor: 21.023

9.  Induction of interleukin-10 by human immunodeficiency virus type 1 and its gp120 protein in human monocytes/macrophages.

Authors:  P Borghi; L Fantuzzi; B Varano; S Gessani; P Puddu; L Conti; M R Capobianchi; F Ameglio; F Belardelli
Journal:  J Virol       Date:  1995-02       Impact factor: 5.103

10.  Type I interferons and interferon regulatory factors regulate TNF-related apoptosis-inducing ligand (TRAIL) in HIV-1-infected macrophages.

Authors:  Yunlong Huang; Angelique Walstrom; Luwen Zhang; Yong Zhao; Min Cui; Ling Ye; Jialin C Zheng
Journal:  PLoS One       Date:  2009-04-30       Impact factor: 3.240
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