Literature DB >> 19206079

Clinical and cost effectiveness of services for early diagnosis and intervention in dementia.

Sube Banerjee1, Raphael Wittenberg.   

Abstract

BACKGROUND: This paper analyses the costs and benefits of commissioning memory services for early diagnosis and intervention for dementia.
METHOD: A model was developed to examine potential public and private savings associated with delayed admissions to care homes in England as a result of the commissioning of memory services.
FINDINGS: The new services would cost around pound sterling 220 million extra per year nationally in England. The estimated savings if 10% of care home admissions were prevented would by year 10 be around pound sterling 120 million in public expenditure (social care) and pound sterling 125 million in private expenditure (service users and their families), a total of pound sterling 245 million. Under a 20% reduction, the annual cost would within around 6 years be offset by the savings to public funds alone. In 10 years all people with dementia will have had the chance to be seen by the new services. A gain of between 0.01 and 0.02 QALYs per person year would be sufficient to render the service cost-effective (in terms of positive net present value). These relatively small improvements seem very likely to be achievable.
INTERPRETATION: These analyses suggest that the service need only achieve a modest increase in average quality of life of people with dementia, plus a 10% diversion of people with dementia from residential care, to be cost-effective. The net increase in public expenditure would then, on the assumptions discussed and from a societal perspective, be justified by the expected benefits. This modelling presents for debate support for the development of nationwide services for the early identification and treatment of dementia in terms of quality of life and overall cost-effectiveness.

Entities:  

Mesh:

Year:  2009        PMID: 19206079     DOI: 10.1002/gps.2191

Source DB:  PubMed          Journal:  Int J Geriatr Psychiatry        ISSN: 0885-6230            Impact factor:   3.485


  44 in total

1.  Quality improvement in neurology: dementia management quality measures.

Authors:  Germaine Odenheimer; Soo Borson; Amy E Sanders; Rebecca J Swain-Eng; Helen H Kyomen; Samantha Tierney; Laura N Gitlin; Mary Ann Forciea; John Absher; Joseph Shega; Jerry Johnson
Journal:  Neurology       Date:  2013-09-25       Impact factor: 9.910

2.  Are memory clinics effective? The odds are in favour of their benefit, but conclusive evidence is not yet available.

Authors:  R J F Melis; E J Meeuwsen; S G Parker; M G M Olde Rikkert
Journal:  J R Soc Med       Date:  2009-11       Impact factor: 5.344

3.  Family and Caregiver Spillover Effects in Cost-Utility Analyses of Alzheimer's Disease Interventions.

Authors:  Pei-Jung Lin; Brittany D'Cruz; Ashley A Leech; Peter J Neumann; Myrlene Sanon Aigbogun; Dorothee Oberdhan; Tara A Lavelle
Journal:  Pharmacoeconomics       Date:  2019-04       Impact factor: 4.981

4.  Early Alert of Elderly Cognitive Impairment using Temporal Streaming Clustering.

Authors:  Omar A Ibrahim; Sunyang Fu; Maria Vassilaki; Ronald C Petersen; Michelle M Mielke; Jennifer St Sauver; Sunghwan Sohn
Journal:  Proceedings (IEEE Int Conf Bioinformatics Biomed)       Date:  2021-12

5.  Developing the New Interventions for independence in Dementia Study (NIDUS) theoretical model for supporting people to live well with dementia at home for longer: a systematic review of theoretical models and Randomised Controlled Trial evidence.

Authors:  Kathryn Lord; Jules Beresford-Dent; Penny Rapaport; Alex Burton; Monica Leverton; Kate Walters; Iain Lang; Murna Downs; Jill Manthorpe; Sue Boex; Joy Jackson; Margaret Ogden; Claudia Cooper
Journal:  Soc Psychiatry Psychiatr Epidemiol       Date:  2019-11-02       Impact factor: 4.328

6.  Effectiveness of an intervention to facilitate prompt referral to memory clinics in the United Kingdom: Cluster randomised controlled trial.

Authors:  Gill Livingston; Gianluca Baio; Andrew Sommerlad; Simon de Lusignan; Spyridon Poulimenos; Steve Morris; Greta Rait; Juanita Hoe
Journal:  PLoS Med       Date:  2017-03-14       Impact factor: 11.069

7.  How, why and under what circumstances does a quality improvement collaborative build knowledge and skills in clinicians working with people with dementia? A realist informed process evaluation.

Authors:  Lenore de la Perrelle; Monica Cations; Gaery Barbery; Gorjana Radisic; Billingsley Kaambwa; Maria Crotty; Janna Anneke Fitzgerald; Susan Kurrle; Ian Cameron; Craig Whitehead; Jane Thompson; Kate Laver
Journal:  BMJ Open Qual       Date:  2021-05

Review 8.  2020 update on the clinical validity of cerebrospinal fluid amyloid, tau, and phospho-tau as biomarkers for Alzheimer's disease in the context of a structured 5-phase development framework.

Authors:  A Leuzy; N J Ashton; N Mattsson-Carlgren; A Dodich; M Boccardi; J Corre; A Drzezga; A Nordberg; R Ossenkoppele; H Zetterberg; K Blennow; G B Frisoni; V Garibotto; O Hansson
Journal:  Eur J Nucl Med Mol Imaging       Date:  2021-03-05       Impact factor: 9.236

9.  Sensitivity and specificity of the Bamberg Dementia Screening Test's (BDST) full and short versions: brief screening instruments for geriatric patients that are suitable for infectious environments.

Authors:  Wolfgang Trapp; Susanne Röder; Andreas Heid; Pia Billman; Susanne Daiber; Göran Hajak
Journal:  BMC Med       Date:  2021-03-05       Impact factor: 8.775

Review 10.  Assessing dementia in resource-poor regions.

Authors:  Gladys E Maestre
Journal:  Curr Neurol Neurosci Rep       Date:  2012-10       Impact factor: 5.081

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