Literature DB >> 1920604

Plasma protein binding of nitroxynil in several species.

M Alvinerie1, R Floc'h, P Galtier.   

Abstract

The binding of nitroxynil to total plasma proteins of cows, sheep and rabbits was characterized using equilibrium dialysis. The data indicate clearly that nitroxynil was highly (97-98%) bound to plasma protein of each animal. This linear binding would be due to the particular power exerted by serum albumin. The results are in good agreement with known pharmacokinetic properties of nitroxynil in domestic species.

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Year:  1991        PMID： 1920604     DOI： 10.1111/j.1365-2885.1991.tb00819.x

Source DB:  PubMed          Journal:  J Vet Pharmacol Ther        ISSN： 0140-7783            Impact factor:   1.786


  5 in total

1.  Fasciola hepatica: tegumental surface alterations following treatment in vivo and in vitro with nitroxynil (Trodax).

Authors:  B McKinstry; I Fairweather; G P Brennan; A B Forbes
Journal:  Parasitol Res       Date:  2003-08-22       Impact factor: 2.289

2.  Fasciola hepatica: effects of the fasciolicide clorsulon in vitro and in vivo on the tegumental surface, and a comparison of the effects on young- and old-mature flukes.

Authors:  M Meaney; I Fairweather; G P Brennan; L S L McDowell; A B Forbes
Journal:  Parasitol Res       Date:  2003-08-22       Impact factor: 2.289

3.  Ultrastructural changes induced in the tegument and gut of Fasciola hepatica following in vivo and in vitro drug treatment with nitroxynil (Trodax).

Authors:  B McKinstry; G P Brennan; L Halferty; A B Forbes; I Fairweather
Journal:  Parasitol Res       Date:  2007-06-08       Impact factor: 2.289

4.  A scanning electron microscope study on the route of entry of clorsulon into the liver fluke, Fasciola hepatica.

Authors:  M Meaney; S Haughey; G P Brennan; I Fairweather
Journal:  Parasitol Res       Date:  2004-12-10       Impact factor: 2.289

5.  Morphological response of triclabendazole-susceptible and triclabendazole-resistant isolates of Fasciola hepatica to treatment in vitro with nitroxynil (Trodax).

Authors:  B McKinstry; L Halferty; G P Brennan; I Fairweather
Journal:  Parasitol Res       Date:  2008-11-18       Impact factor: 2.289
  5 in total

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