Isolated sinonasal sarcoidosis with intracranial extension: case report.

The case is presented of a 20-year-old female who was incidentally diagnosed with isolated sarcoidosis in the form of a nasal mass involving the ethmoid sinuses with destruction of the cribriform plate and intracranial extension. The patient complained of cacosmia and nasal obstruction. Histopathologic examination of biopsies from the nasal mass led to a diagnosis of non-caseating granuloma, highly suggestive of sarcoidosis. No systemic manifestations were detected, and the patient was started on a regimen of systemic steroids. Over the 3 months following biopsy and commencement of systemic steroids, the patient showed improvement in symptoms, and computed tomography of the paranasal sinuses revealed complete resolution of the sinonasal mass. Follow-up for one year revealed no recurrence.