| Literature DB >> 19203831 |
Ho-Keun Kwon1, Won Kyung Jeon2, Ji-Sun Hwang1, Choong-Gu Lee1, Jae-Seon So1, Jin-A Park1, Byoung Seob Ko2, Sin-Hyeog Im3.
Abstract
Cinnamon is one of the most widely used herbal medicines with diverse bioactive effects. However, little evidence has been reported about the potential anti-tumor effects of cinnamon. In vitro and in vivo system, cinnamon treatment strongly inhibited the expression of pro-angiogenic factors and master regulators of tumor progression not only in melanoma cell lines but also in experimental melanoma model. In addition, cinnamon treatment increased the anti-tumor activities of CD8(+) T cells by increasing the levels of cytolytic molecules and their cytotoxic activity. In conclusion, cinnamon extract has the potential to be an alternative medicine for tumor treatment.Entities:
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Year: 2009 PMID： 19203831 DOI： 10.1016/j.canlet.2009.01.015
Source DB: PubMed Journal: Cancer Lett ISSN： 0304-3835 Impact factor: 8.679