| Literature DB >> 19203571 |
Ran Kafri1, Michael Springer, Yitzhak Pilpel.
Abstract
Many crucial components of signal transduction, developmental, and metabolic pathways have functionally redundant copies. Further, these redundancies show surprising evolutionary stability over prolonged time scales. We propose that redundancies are not just archeological leftovers of ancient gene duplications, but rather that synergy arising from feedback between redundant copies may serve as an information processing element that facilitates signal transduction and the control of gene expression.Mesh：
Year: 2009 PMID： 19203571 DOI： 10.1016/j.cell.2009.01.027
Source DB: PubMed Journal: Cell ISSN： 0092-8674 Impact factor: 41.582