Literature DB >> 19203247

Benzophenone derivatives from the fruits of Garcinia multiflora and their anti-inflammatory activity.

Jih-Jung Chen1, Chia-Wei Ting, Tsong-Long Hwang, Ih-Sheng Chen.   

Abstract

Five new benzophenone derivatives, 13,14-didehydoxyisogarcinol (1), garcimultiflorone A (2), garcimultiflorone B (3), 13-hydroxygarcimultiflorone B (4), and garcimultiflorone C (5), have been isolated from the fruits of Garcinia multiflora, together with seven known compounds (6-12). The structures of these new compounds were determined through spectroscopic and MS analyses. 13,14-Didehydoxyisogarcinol (1), garcimultiflorone A (2), garcimultiflorone B (3), and 13-hydroxygarcimultiflorone B (4) exhibited inhibition with an IC(50) range of 0.11-5.58 microM on superoxide anion generation and elastase release by human neutrophils in response to fMet-Leu-Phe/cytochalasin B (fMLP/CB).

Entities:  

Mesh：

Substances：

Year:  2009        PMID： 19203247     DOI： 10.1021/np8006364

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  8 in total

1.  Regiodivergent Photocyclization of Dearomatized Acylphloroglucinols: Asymmetric Syntheses of (-)-Nemorosone and (-)-6-epi-Garcimultiflorone A.

Authors:  Saishuai Wen; Jonathan H Boyce; Sunil K Kandappa; Jayaraman Sivaguru; John A Porco
Journal:  J Am Chem Soc       Date:  2019-07-02       Impact factor: 15.419

2.  Syntheses of (+)-30-epi-, (-)-6-epi-, (±)-6,30-epi-13,14-Didehydroxyisogarcinol and (±)-6,30-epi-Garcimultiflorone A Utilizing Highly Diastereoselective, Lewis Acid-Controlled Cyclizations.

Authors:  Jonathan H Boyce; Vincent Eschenbrenner-Lux; John A Porco
Journal:  J Am Chem Soc       Date:  2016-10-27       Impact factor: 15.419

3.  Studies on the interaction between benzophenone and bovine serum albumin by spectroscopic methods.

Authors:  Ye-Zhong Zhang; Jing Zhang; Fang-Fang Li; Xun Xiang; A-Qiong Ren; Yi Liu
Journal:  Mol Biol Rep       Date:  2010-11-19       Impact factor: 2.316

Review 4.  Antagonism of human formyl peptide receptor 1 with natural compounds and their synthetic derivatives.

Authors:  Igor A Schepetkin; Andrei I Khlebnikov; Liliya N Kirpotina; Mark T Quinn
Journal:  Int Immunopharmacol       Date:  2015-09-15       Impact factor: 4.932

5.  The natural compound Guttiferone F sensitizes prostate cancer to starvation induced apoptosis via calcium and JNK elevation.

Authors:  Xin Li; Yuanzhi Lao; Hong Zhang; Xiaoyu Wang; Hongsheng Tan; Zhixiu Lin; Hongxi Xu
Journal:  BMC Cancer       Date:  2015-04-11       Impact factor: 4.430

6.  Preussianone, a new flavanone-chromone biflavonoid from Garcinia preussii Engl.

Authors:  Bernadette Biloa Messi; Karine Ndjoko-Ioset; Barbara Hertlein-Amslinger; Alain Meli Lannang; Augustin E Nkengfack; Jean-Luc Wolfender; Kurt Hostettmann; Gerhard Bringmann
Journal:  Molecules       Date:  2012-05-21       Impact factor: 4.411

7.  Adamantyl and homoadamantyl derivatives from Garcinia multiflora fruits.

Authors:  Yu Chen; Ziyu Ma; Haida Teng; Fei Gan; Hui Xiong; Zhinan Mei; Guangzhong Yang
Journal:  RSC Adv       Date:  2019-04-17       Impact factor: 3.361

8.  Acylphloroglucinol Derivatives from Garcinia multiflora with Anti-Inflammatory Effect in LPS-Induced RAW264.7 Macrophages.

Authors:  Lin-Yang Cheng; Yun-Chen Tsai; Shu-Ling Fu; Ming-Jen Cheng; Ping-Jyun Sung; Mei-Ing Chung; Jih-Jung Chen
Journal:  Molecules       Date:  2018-10-10       Impact factor: 4.411
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.