Literature DB >> 19203090

The beta cell population in type 1 diabetes.

Daniel Pipeleers1, Peter In't Veld, Miriam Pipeleers-Marichal, Frans Gorus.   

Abstract

Type 1 diabetes is often considered as a disease where more than 90% of the beta cells have been destroyed at clinical onset and where beta cell antigen-driven autoimmune reactivities progressively destroy remaining beta cells as well as newly formed or implanted beta cells. This view will be evaluated in light of histological observations in the pancreas of type 1 diabetic patients and of antibody-positive non-diabetic organ donors.

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Year:  2008        PMID： 19203090     DOI： 10.1002/9780470697405.ch3

Source DB:  PubMed          Journal:  Novartis Found Symp        ISSN： 1528-2511


  10 in total

1.  99th Dahlem conference on infection, inflammation and chronic inflammatory disorders: viruses, autoimmunity and immunoregulation.

Authors:  C M Filippi; M G von Herrath
Journal:  Clin Exp Immunol       Date:  2010-04       Impact factor: 4.330

2.  Diabetes: A virus-gene collaboration.

Authors:  Matthias von Herrath
Journal:  Nature       Date:  2009-05-28       Impact factor: 49.962

Review 3.  Organ donor specimens: What can they tell us about type 1 diabetes?

Authors:  Martha Campbell-Thompson
Journal:  Pediatr Diabetes       Date:  2015-05-22       Impact factor: 4.866

4.  Residual β cell function and monogenic variants in long-duration type 1 diabetes patients.

Authors:  Marc Gregory Yu; Hillary A Keenan; Hetal S Shah; Scott G Frodsham; David Pober; Zhiheng He; Emily A Wolfson; Stephanie D'Eon; Liane J Tinsley; Susan Bonner-Weir; Marcus G Pezzolesi; George Liang King
Journal:  J Clin Invest       Date:  2019-07-02       Impact factor: 14.808

5.  Residual insulin production and pancreatic ß-cell turnover after 50 years of diabetes: Joslin Medalist Study.

Authors:  Hillary A Keenan; Jennifer K Sun; Jared Levine; Alessandro Doria; Lloyd P Aiello; George Eisenbarth; Susan Bonner-Weir; George L King
Journal:  Diabetes       Date:  2010-08-10       Impact factor: 9.461

6.  Histopathology of type 1 diabetes: old paradigms and new insights.

Authors:  Ken T Coppieters; Matthias G von Herrath
Journal:  Rev Diabet Stud       Date:  2009-08-10

7.  Four-year metabolic outcome of a randomised controlled CD3-antibody trial in recent-onset type 1 diabetic patients depends on their age and baseline residual beta cell mass.

Authors:  B Keymeulen; M Walter; C Mathieu; L Kaufman; F Gorus; R Hilbrands; E Vandemeulebroucke; U Van de Velde; L Crenier; C De Block; S Candon; H Waldmann; A G Ziegler; L Chatenoud; D Pipeleers
Journal:  Diabetologia       Date:  2010-01-14       Impact factor: 10.122

8.  Demonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients.

Authors:  Ken T Coppieters; Francesco Dotta; Natalie Amirian; Peter D Campbell; Thomas W H Kay; Mark A Atkinson; Bart O Roep; Matthias G von Herrath
Journal:  J Exp Med       Date:  2012-01-02       Impact factor: 14.307

9.  PET Imaging of Pancreatic Dopamine D2 and D3 Receptor Density with 11C-(+)-PHNO in Type 1 Diabetes.

Authors:  Jason Bini; Elizabeth Sanchez-Rangel; Jean-Dominique Gallezot; Mika Naganawa; Nabeel Nabulsi; Keunpoong Lim; Soheila Najafzadeh; Anupama Shirali; Jim Ropchan; David Matuskey; Yiyun Huang; Kevan C Herold; Paul E Harris; Robert S Sherwin; Richard E Carson; Gary W Cline
Journal:  J Nucl Med       Date:  2019-10-10       Impact factor: 11.082

10.  ZnT8 is a major CD8+ T cell-recognized autoantigen in pediatric type 1 diabetes.

Authors:  Émmanuelle Énée; Roland Kratzer; Jean-Baptiste Arnoux; Emilie Barilleau; Yamina Hamel; Christophe Marchi; Jacques Beltrand; Bénédicte Michaud; Lucienne Chatenoud; Jean-Jacques Robert; Peter van Endert
Journal:  Diabetes       Date:  2012-05-14       Impact factor: 9.461
  10 in total

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