| Literature DB >> 19199662 |
Ayhan S Demir1, Lker Esiringü, Mehmet Göllü, Omer Reis.
Abstract
The first catalytic intermolecular aldehyde-ketone coupling via acyl phosphonate is reported. Acyl phosphonates are potent acyl anion precursors, which generate acyl anion equivalents under the influence of cyanide anion via phosphonate-phosphate rearrangement. These anions readily react with activated ketones to form acyloin type coupling in 41-95% yields.Entities:
Mesh：
Substances：
Year: 2009 PMID： 19199662 DOI： 10.1021/jo8026627
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354