| Literature DB >> 19199323 |
Peng Yang1, Anne De Cian, Marie-Paule Teulade-Fichou, Jean-Louis Mergny, David Monchaud.
Abstract
Lighting up: A G-quadruplex-specific fluorescent probe was designed combining the specificity of the pyridodicarboxamide motif for guanine quadruplexes and the fluorescence properties of thiazole orange. While the assembly of the two partners through a flexible linker leads to a nonselective probe, merging them in a single, rigid scaffold leads to a dye that elicits the properties required for G-quadruplex sensing.Entities:
Mesh:
Substances:
Year: 2009 PMID: 19199323 DOI: 10.1002/anie.200805613
Source DB: PubMed Journal: Angew Chem Int Ed Engl ISSN: 1433-7851 Impact factor: 15.336