Literature DB >> 19199323

Engineering bisquinolinium/thiazole orange conjugates for fluorescent sensing of G-quadruplex DNA.

Peng Yang1, Anne De Cian, Marie-Paule Teulade-Fichou, Jean-Louis Mergny, David Monchaud.   

Abstract

Lighting up: A G-quadruplex-specific fluorescent probe was designed combining the specificity of the pyridodicarboxamide motif for guanine quadruplexes and the fluorescence properties of thiazole orange. While the assembly of the two partners through a flexible linker leads to a nonselective probe, merging them in a single, rigid scaffold leads to a dye that elicits the properties required for G-quadruplex sensing.

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Year:  2009        PMID: 19199323     DOI: 10.1002/anie.200805613

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN: 1433-7851            Impact factor:   15.336


  21 in total

1.  Pyridine Derivative of the Natural Alkaloid Berberine as Human Telomeric G4-DNA Binder: A Solution and Solid-State Study.

Authors:  Francesco Papi; Carla Bazzicalupi; Marta Ferraroni; Giulia Ciolli; Paolo Lombardi; Asma Yasmeen Khan; Gopinatha Suresh Kumar; Paola Gratteri
Journal:  ACS Med Chem Lett       Date:  2020-02-07       Impact factor: 4.345

2.  Second Generation G-Quadruplex Stabilizing Trimethine Cyanines.

Authors:  Eric A Owens; Hang T Huynh; Ekaterina M Stroeva; Arghya Barman; Kostiantyn Ziabrev; Ananya Paul; Sarah V Nguyen; Matthew Laramie; Donald Hamelberg; Markus W Germann; W David Wilson; Maged Henary
Journal:  Bioconjug Chem       Date:  2019-09-26       Impact factor: 4.774

3.  Mono and trimethine cyanines Cyan 40 and Cyan 2 as probes for highly selective fluorescent detection of non-canonical DNA structures.

Authors:  Vladyslava B Kovalska; Mykhaylo Yu Losytskyy; Sergiy M Yarmoluk; Irit Lubitz; Alexander B Kotlyar
Journal:  J Fluoresc       Date:  2010-09-01       Impact factor: 2.217

Review 4.  Modulation of DNA structure formation using small molecules.

Authors:  Imee M A Del Mundo; Karen M Vasquez; Guliang Wang
Journal:  Biochim Biophys Acta Mol Cell Res       Date:  2019-09-03       Impact factor: 4.739

5.  An assay for human telomeric G-quadruplex DNA binding drugs.

Authors:  Derrick Watkins; Nihar Ranjan; Sunil Kumar; Changjun Gong; Dev P Arya
Journal:  Bioorg Med Chem Lett       Date:  2013-11-01       Impact factor: 2.823

6.  More is not always better: finding the right trade-off between affinity and selectivity of a G-quadruplex ligand.

Authors:  Michela Zuffo; Aurore Guédin; Emma-Dune Leriche; Filippo Doria; Valentina Pirota; Valérie Gabelica; Jean-Louis Mergny; Mauro Freccero
Journal:  Nucleic Acids Res       Date:  2018-11-02       Impact factor: 16.971

7.  Berberrubine Phosphate: A Selective Fluorescent Probe for Quadruplex DNA.

Authors:  Peter Jonas Wickhorst; Heiko Ihmels
Journal:  Molecules       Date:  2021-04-28       Impact factor: 4.411

8.  A new cationic porphyrin derivative (TMPipEOPP) with large side arm substituents: a highly selective G-quadruplex optical probe.

Authors:  Li-Na Zhu; Shu-Juan Zhao; Bin Wu; Xiao-Zeng Li; De-Ming Kong
Journal:  PLoS One       Date:  2012-05-22       Impact factor: 3.240

9.  An acetylene-bridged 6,8-purine dimer as a fluorescent switch-on probe for parallel G-quadruplexes.

Authors:  Mehran Nikan; Marco Di Antonio; Keren Abecassis; Keith McLuckie; Shankar Balasubramanian
Journal:  Angew Chem Int Ed Engl       Date:  2012-12-13       Impact factor: 15.336

Review 10.  Broad Applications of Thiazole Orange in Fluorescent Sensing of Biomolecules and Ions.

Authors:  Ohad Suss; Leila Motiei; David Margulies
Journal:  Molecules       Date:  2021-05-10       Impact factor: 4.411

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