| Literature DB >> 19198630 |
Anja Schüffler1, Daniela Kautz, Johannes C Liermann, Till Opatz, Timm Anke.
Abstract
In a screening for new bioactive compounds, the extract of Allantophomopsis lycopodina strain IBWF58B-05A, an imperfect ascomycete, was found to exhibit strong but rather selective antibiotic activity against Paecilomyces variotii. The bioactivity-guided isolation yielded allantofuranone, a new and uncommon gamma-lactone. This compound showed antifungal activity against P. variotii and Penicillium species. This paper describes the isolation, structure elucidation and biological characteristics of allantofuranone.Entities:
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Year: 2009 PMID： 19198630 DOI： 10.1038/ja.2008.21
Source DB: PubMed Journal: J Antibiot (Tokyo) ISSN： 0021-8820 Impact factor: 2.649