Literature DB >> 19198066

Ubiquitination of Myc: proteasomal degradation and beyond.

J Müller1, M Eilers.   

Abstract

The level of Myc proteins is a critical determinant of cellular proliferation and apoptosis. Ubiquitination of Myc plays a key role in controlling protein levels by stimulating proteasomal degradation of the protein. Some experiments suggest that ubiquitination may also regulate Myc function in addition to turnover. This review attempts to summarize current knowledge about this field.

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Year:  2008        PMID： 19198066     DOI： 10.1007/2789_2008_103

Source DB:  PubMed          Journal:  Ernst Schering Found Symp Proc


  9 in total

1.  Expression of the novel human gene, UBE2Q1, in breast tumors.

Authors:  Atefeh Seghatoleslam; Mohsen Nikseresht; Sayed Mohammad Shafiee; Ahmad Monabati; Mohammad Mehdi Namavari; Abdolrassul Talei; Akbar Safaei; Ali Akbar Owji
Journal:  Mol Biol Rep       Date:  2011-12-14       Impact factor: 2.316

2.  Domain-specific c-Myc ubiquitylation controls c-Myc transcriptional and apoptotic activity.

Authors:  Qin Zhang; Erick Spears; David N Boone; Zhaoliang Li; Mark A Gregory; Stephen R Hann
Journal:  Proc Natl Acad Sci U S A       Date:  2012-12-31       Impact factor: 11.205

3.  Noninvasive molecular imaging of c-Myc activation in living mice.

Authors:  Hua Fan-Minogue; Zhongwei Cao; Ramasamy Paulmurugan; Carmel T Chan; Tarik F Massoud; Dean W Felsher; Sanjiv S Gambhir
Journal:  Proc Natl Acad Sci U S A       Date:  2010-08-16       Impact factor: 11.205

4.  Role of Pirh2 in mediating the regulation of p53 and c-Myc.

Authors:  Anne Hakem; Miyuki Bohgaki; Bénédicte Lemmers; Elisabeth Tai; Leonardo Salmena; Elzbieta Matysiak-Zablocki; Yong-Sam Jung; Jana Karaskova; Lilia Kaustov; Shili Duan; Jason Madore; Paul Boutros; Yi Sheng; Marta Chesi; P Leif Bergsagel; Bayardo Perez-Ordonez; Anne-Marie Mes-Masson; Linda Penn; Jeremy Squire; Xinbin Chen; Igor Jurisica; Cheryl Arrowsmith; Otto Sanchez; Samuel Benchimol; Razqallah Hakem
Journal:  PLoS Genet       Date:  2011-11-17       Impact factor: 5.917

5.  Clinical significance of high c-MYC and low MYCBP2 expression and their association with Ikaros dysfunction in adult acute lymphoblastic leukemia.

Authors:  Zheng Ge; Xing Guo; Jianyong Li; Melanie Hartman; Yuka Imamura Kawasawa; Sinisa Dovat; Chunhua Song
Journal:  Oncotarget       Date:  2015-12-08

6.  LncRNA CSMD1-1 promotes the progression of Hepatocellular Carcinoma by activating MYC signaling.

Authors:  Ji Liu; Rui Xu; Shi-Juan Mai; Yu-Shui Ma; Mei-Yin Zhang; Ping-Sheng Cao; Nuo-Qing Weng; Rui-Qi Wang; Di Cao; Wei Wei; Rong-Ping Guo; Yao-Jun Zhang; Li Xu; Min-Shan Chen; Hui-Zhong Zhang; Long Huang; Da Fu; Hui-Yun Wang
Journal:  Theranostics       Date:  2020-06-12       Impact factor: 11.556

7.  Crystal Structures and Nuclear Magnetic Resonance Studies of the Apo Form of the c-MYC:MAX bHLHZip Complex Reveal a Helical Basic Region in the Absence of DNA.

Authors:  Susan Sammak; Najoua Hamdani; Fabrice Gorrec; Mark D Allen; Stefan M V Freund; Mark Bycroft; Giovanna Zinzalla
Journal:  Biochemistry       Date:  2019-07-11       Impact factor: 3.162

8.  Mule/Huwe1/Arf-BP1 suppresses Ras-driven tumorigenesis by preventing c-Myc/Miz1-mediated down-regulation of p21 and p15.

Authors:  Satoshi Inoue; Zhenyue Hao; Andrew J Elia; David Cescon; Lily Zhou; Jennifer Silvester; Bryan Snow; Isaac S Harris; Masato Sasaki; Wanda Y Li; Momoe Itsumi; Kazuo Yamamoto; Takeshi Ueda; Carmen Dominguez-Brauer; Chiara Gorrini; Iok In Christine Chio; Jillian Haight; Annick You-Ten; Susan McCracken; Andrew Wakeham; Danny Ghazarian; Linda J Z Penn; Gerry Melino; Tak W Mak
Journal:  Genes Dev       Date:  2013-05-15       Impact factor: 11.361

Review 9.  Structural and Biophysical Insights into the Function of the Intrinsically Disordered Myc Oncoprotein.

Authors:  Marie-Eve Beaulieu; Francisco Castillo; Laura Soucek
Journal:  Cells       Date:  2020-04-22       Impact factor: 6.600
  9 in total

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