| Literature DB >> 19196200 |
Fernanda A Dorella1, Luis Gc Pacheco, Núbia Seyffert, Ricardo W Portela, Roberto Meyer, Anderson Miyoshi, Vasco Azevedo.
Abstract
Corynebacterium pseudotuberculosis continues to cause considerable economic losses in ovine and caprine herds worldwide, causing caseous lymphadenitis. Nevertheless, the immunology of this disease is relatively unknown. Novel antigens may provide vaccines that are more effective and improve diagnostic methods for better control of this disease. The available commercial vaccines are not able to fully protect susceptible animals, cannot be used in all host species and are not licensed for use in many countries. Recent studies on the genomics of C. pseudotuberculosis and on its molecular determinants of virulence should bring us new alternatives for more effective vaccine formulations.Entities:
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Year: 2009 PMID: 19196200 DOI: 10.1586/14760584.8.2.205
Source DB: PubMed Journal: Expert Rev Vaccines ISSN: 1476-0584 Impact factor: 5.217