| Literature DB >> 1919600 |
F Duarte1, S Binet, L Lacomblez, P Bouche, J L Preud'homme, V Meininger.
Abstract
In a prospective study, we analysed the presence of monoclonal immunoglobulin (moIg) in the serum from 30 patients with amyotrophic lateral sclerosis (ALS) and 30 matched controls using a sensitive Western blot technique. The incidence of serum moIg was 60% in the ALS group and 13.3% in the control group. Most ALS sera contained 2 or 3 monoclonal components. They were IgG (72.7%) and IgM (27.3%). These results corroborate the concept of a probable association between ALS and serum moIg.Entities:
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Year: 1991 PMID： 1919600 DOI： 10.1016/0022-510x(91)90220-2
Source DB: PubMed Journal: J Neurol Sci ISSN： 0022-510X Impact factor: 3.181