| Literature DB >> 1919591 |
Abstract
Microbial metabolism of the diterpene sclareol was studied. Screening studies have shown a number of microorganisms capable of metabolizing sclareol. Preparative scale fermentation with Cunninghamella species NRRL 5695 has resulted in the production of two fungal metabolites that have been characterized as 3 beta-hydroxysclareol and 18-hydroxy-sclareol with the use of 2D nmr techniques. The yield of the two metabolites was improved by utilizing resting-cell suspensions of Cunninghamella species NRRL 5695.Entities:
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Year: 1991 PMID: 1919591 DOI: 10.1021/np50074a021
Source DB: PubMed Journal: J Nat Prod ISSN: 0163-3864 Impact factor: 4.050