Literature DB >> 1919590

Plant metabolites. New compounds and anti-inflammatory activity of Uncaria tomentosa.

R Aquino1, V De Feo, F De Simone, C Pizza, G Cirino.   

Abstract

Bioassay-directed fractionation of the anti-inflammatory extracts of Uncaria tomentosa, using the carrageenan-induced edema in rat paw, has led to the isolation of a new quinovic acid glycoside 7 as one of the active principles. Furthermore, a new triterpene 8 was isolated as its methyl ester. The structures were elucidated by spectral and chemical studies.

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Year:  1991        PMID： 1919590     DOI： 10.1021/np50074a016

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  9 in total

1.  The Quinovic Acid Glycosides Purified Fraction from Uncaria tomentosa Protects against Hemorrhagic Cystitis Induced by Cyclophosphamide in Mice.

Authors:  Fabrícia Dietrich; Jerônimo Pietrobon Martins; Samuel Kaiser; Rodrigo Braccini Madeira Silva; Liliana Rockenbach; Maria Isabel Albano Edelweiss; George González Ortega; Fernanda Bueno Morrone; Maria Martha Campos; Ana Maria Oliveira Battastini
Journal:  PLoS One       Date:  2015-07-08       Impact factor: 3.240

Review 2.  Root Canal Irrigation: Chemical Agents and Plant Extracts Against Enterococcus faecalis.

Authors:  Letizia Borzini; Roberta Condò; Paolo De Dominicis; Adriano Casaglia; Loredana Cerroni
Journal:  Open Dent J       Date:  2016-12-19

3.  Decrease in Dengue virus-2 infection and reduction of cytokine/chemokine production by Uncaria guianensis in human hepatocyte cell line Huh-7.

Authors:  Cíntia da Silva Mello; Ligia Maria Marino Valente; Thiago Wolff; Raimundo Sousa Lima-Junior; Luciana Gomes Fialho; Cintia Ferreira Marinho; Elzinandes Leal Azeredo; Luzia Maria Oliveira-Pinto; Rita de Cássia Alves Pereira; Antonio Carlos Siani; Claire Fernandes Kubelka
Journal:  Mem Inst Oswaldo Cruz       Date:  2017-06       Impact factor: 2.743

Review 4.  Anti-Inflammatory Activity of Natural Products.

Authors:  Abdullatif Azab; Ahmad Nassar; Abed N Azab
Journal:  Molecules       Date:  2016-10-01       Impact factor: 4.411

5.  The Amazon rain forest plant Uncaria tomentosa (cat's claw) and its specific proanthocyanidin constituents are potent inhibitors and reducers of both brain plaques and tangles.

Authors:  Alan D Snow; Gerardo M Castillo; Beth P Nguyen; Paula Y Choi; Joel A Cummings; Judy Cam; Qubai Hu; Thomas Lake; Weihong Pan; Abba J Kastin; Daniel A Kirschner; Steven G Wood; Edward Rockenstein; Eliezer Masliah; Stephen Lorimer; Rudolph E Tanzi; Lesley Larsen
Journal:  Sci Rep       Date:  2019-02-06       Impact factor: 4.379

6.  Quinovic Acid Impedes Cholesterol Dyshomeostasis, Oxidative Stress, and Neurodegeneration in an Amyloid-β-Induced Mouse Model.

Authors:  Kamran Saeed; Shahid Ali Shah; Rahat Ullah; Sayed Ibrar Alam; Jun Sung Park; Samreen Saleem; Myeung Hoon Jo; Min Woo Kim; Jong Ryeal Hahm; Myeong Ok Kim
Journal:  Oxid Med Cell Longev       Date:  2020-11-20       Impact factor: 6.543

7.  Treatment with Uncaria tomentosa Promotes Apoptosis in B16-BL6 Mouse Melanoma Cells and Inhibits the Growth of B16-BL6 Tumours.

Authors:  Ali Zari; Hajer Alfarteesh; Carly Buckner; Robert Lafrenie
Journal:  Molecules       Date:  2021-02-18       Impact factor: 4.411

8.  Uncaria tomentosa exerts extensive anti-neoplastic effects against the Walker-256 tumour by modulating oxidative stress and not by alkaloid activity.

Authors:  Arturo Alejandro Dreifuss; Amanda Leite Bastos-Pereira; Isabella Aviles Fabossi; Francislaine Aparecida Dos Reis Lívero; Aline Maria Stolf; Carlos Eduardo Alves de Souza; Liana de Oliveira Gomes; Rodrigo Polimeni Constantin; Aline Emmer Ferreira Furman; Regiane Lauriano Batista Strapasson; Simone Teixeira; Aleksander Roberto Zampronio; Marcelo Nicolás Muscará; Maria Elida Alves Stefanello; Alexandra Acco
Journal:  PLoS One       Date:  2013-02-07       Impact factor: 3.240

9.  Bioactivity-Guided Separation of Anti-Cholinesterase Alkaloids from Uncaria rhynchophlly (Miq.) Miq. Ex Havil Based on HSCCC Coupled with Molecular Docking.

Authors:  Pengfei Yu; Zhenshan Chen; Yuecheng Liu; Zhengwei Gu; Xiaoming Wang; Yaowen Zhang; Yanni Ma; Meiyue Dong; Zhenhua Tian
Journal:  Molecules       Date:  2022-03-21       Impact factor: 4.411
  9 in total

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