Literature DB >> 19195800

Fluoromethcathinone, a new substance of abuse.

R P Archer1.   

Abstract

We have identified a new compound in capsules marketed as plant feeders available from internet suppliers. It is apparent from internet forums that these so-called plant feeders are being used as recreational drugs. The material is identified as being 3'-fluoromethcathinone. The compound in the capsule was identified by GC-MS, 1H, (13)C and (19)F NMR as well as FTIR. Other materials identified in the tablet were caffeine and a methylamine salt. The exact position of the fluorine in the fluoromethcathinone was determined by comparison with materials synthesised in our laboratory. Internet-based companies are known to sell 4'-fluoromethcathinone (flephedrone). We present GC-MS data for the three isomers of fluoromethcathinone and their N-acetyl derivatives and provide a rapid method for determining the positional isomers of fluoromethcathinone using FTIR or (19)F NMR.

Entities:  

Year:  2009        PMID: 19195800     DOI: 10.1016/j.forsciint.2008.11.013

Source DB:  PubMed          Journal:  Forensic Sci Int        ISSN: 0379-0738            Impact factor:   2.395


  12 in total

1.  Structure-Activity Relationships of Substituted Cathinones, with Transporter Binding, Uptake, and Release.

Authors:  Amy J Eshleman; Katherine M Wolfrum; John F Reed; Sunyoung O Kim; Tracy Swanson; Robert A Johnson; Aaron Janowsky
Journal:  J Pharmacol Exp Ther       Date:  2016-10-31       Impact factor: 4.030

Review 2.  The toxicology of bath salts: a review of synthetic cathinones.

Authors:  Jane M Prosser; Lewis S Nelson
Journal:  J Med Toxicol       Date:  2012-03

3.  Conformational analysis of flephedrone using quantum mechanical models.

Authors:  Wojciech Kolodziejczyk; Jerzy Jodkowski; Tiffani M Holmes; Glake A Hill
Journal:  J Mol Model       Date:  2012-12-14       Impact factor: 1.810

4.  Quantitative structure-activity relationship analysis of the pharmacology of para-substituted methcathinone analogues.

Authors:  J S Bonano; M L Banks; R Kolanos; F Sakloth; M L Barnier; R A Glennon; N V Cozzi; J S Partilla; M H Baumann; S S Negus
Journal:  Br J Pharmacol       Date:  2015-04-10       Impact factor: 8.739

5.  Studies on the phase I metabolism of the new designer drug 3-fluoromethcathinone using rabbit liver slices.

Authors:  Evelyn Pawlik; Gerd Plässer; Hellmut Mahler; Thomas Daldrup
Journal:  Int J Legal Med       Date:  2011-07-23       Impact factor: 2.686

Review 6.  Mephedrone (4-methylmethcathinone; 'meow meow'): chemical, pharmacological and clinical issues.

Authors:  Fabrizio Schifano; Antonio Albanese; Suzanne Fergus; Jackie L Stair; Paolo Deluca; Ornella Corazza; Zoe Davey; John Corkery; Holger Siemann; Norbert Scherbaum; Magi' Farre'; Marta Torrens; Zsolt Demetrovics; A Hamid Ghodse
Journal:  Psychopharmacology (Berl)       Date:  2010-11-12       Impact factor: 4.530

Review 7.  Emerging drugs of abuse: current perspectives on substituted cathinones.

Authors:  Magalie Paillet-Loilier; Alexandre Cesbron; Reynald Le Boisselier; Joanna Bourgine; Danièle Debruyne
Journal:  Subst Abuse Rehabil       Date:  2014-05-26

Review 8.  Neurotoxicity Induced by Mephedrone: An up-to-date Review.

Authors:  Flaminia Pantano; Roberta Tittarelli; Giulio Mannocchi; Roberta Pacifici; Alessandro di Luca; Francesco Paolo Busardò; Enrico Marinelli
Journal:  Curr Neuropharmacol       Date:  2017       Impact factor: 7.363

9.  Para-Halogenation of Amphetamine and Methcathinone Increases the Mitochondrial Toxicity in Undifferentiated and Differentiated SH-SY5Y Cells.

Authors:  Xun Zhou; Jamal Bouitbir; Matthias E Liechti; Stephan Krähenbühl; Riccardo V Mancuso
Journal:  Int J Mol Sci       Date:  2020-04-18       Impact factor: 5.923

10.  Characterization of a recently detected halogenated aminorex derivative: para-fluoro-4-methylaminorex (4'F-4-MAR).

Authors:  D Fabregat-Safont; X Carbón; M Ventura; I Fornís; F Hernández; M Ibáñez
Journal:  Sci Rep       Date:  2019-06-05       Impact factor: 4.379

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