Literature DB >> 19195764

Feasibility and morbidity of using saline filled tissue expanders to reduce radiation-induced bowel injury in patients with gynecologic malignancies.

Melissa A Geller1, Peter A Argenta, Sajeena G Thomas, Kathryn E Dusenbery, Patricia L Judson, Matthew P Boente.   

Abstract

OBJECTIVES: To evaluate the feasibility and morbidity of using saline filled tissue expanders (TE) to displace the small bowel during radiation therapy in patients with gynecologic malignancies. STUDY
DESIGN: Ten patients undergoing surgical exploration for a gynecologic malignancy and deemed to be at high risk for the late effects of radiation therapy were consented for the possible placement of a TE. Indication for placement was need for post-operative radiation. Small bowel exclusion was reported in terms of the lowest loop identified on treatment planning film using orally ingested barium.
RESULTS: Small bowel loops were excluded from the pelvis to varying degrees in all patients. Lowest identifiable bowel was marked at the L4-L5 interspace in one patient, L5-S1 interspace in three patients, at or near the sacral promontory in three patients, and to the middle of S2 in one patient. In two patients the TE was removed prior to simulation. Early complications included migration of the TE during treatment, development of a vesicovaginal fistula requiring immediate removal of the TE, and enterocutaneous fistula formation in a patient who developed an abscess following treatment completion. Another patient experienced a rectovaginal fistula 18 months after removal of the TE.
CONCLUSIONS: TE placement can successfully isolate small bowel from the pelvis. Usage should be individualized to minimize the likelihood of short and long-term complications, particularly in patients at higher risk of morbidity.

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Year:  2009        PMID: 19195764     DOI: 10.1016/j.ejogrb.2008.12.013

Source DB:  PubMed          Journal:  Eur J Obstet Gynecol Reprod Biol        ISSN: 0301-2115            Impact factor:   2.435


  3 in total

1.  Tissue expanders: early experience of a novel treatment option for perineal herniation.

Authors:  J M Ali; A Stabler; N R Hall; M Irwin; R Miller; N S Fearnhead
Journal:  Hernia       Date:  2012-06-28       Impact factor: 4.739

2.  Chemotherapy and patient co-morbidity in ventral site hernia development.

Authors:  Mark A Rettenmaier; Lisa N Abaid; John V Brown; John P Micha; Bram H Goldstein
Journal:  J Gynecol Oncol       Date:  2009-12-28       Impact factor: 4.401

3.  Use of a tissue expander to protect small bowel during radiotherapy in a cervical cancer patient with severe Crohn's disease.

Authors:  Sarah Ravn; Robert Pearcey; Valerie Capstick
Journal:  Gynecol Oncol Rep       Date:  2015-09-04
  3 in total

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