| Literature DB >> 1919532 |
J G Calvert1, E Nagy, M Soler, P Dobos.
Abstract
By the use of strong denaturing agents, a genome-linked protein (VPg)-RNA complex was purified from infectious pancreatic necrosis virus. Ribonuclease treatment of 125I-labelled VPg-RNA released a 90K polypeptide identical to the minor structural polypeptide VP1 (the putative RNA polymerase), as determined by peptide mapping. The polypeptide is linked to the RNA by a serine-5' GMP phosphodiester bond. The results identify birnaviruses as the only dsRNA viruses with a VPg, the size of which is the largest of the VPgs of RNA viruses.Entities:
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Year: 1991 PMID： 1919532 DOI： 10.1099/0022-1317-72-10-2563
Source DB: PubMed Journal: J Gen Virol ISSN： 0022-1317 Impact factor: 3.891