Literature DB >> 19193988

Structure of the thioredoxin-fold domain of human phosducin-like protein 2.

Xiaochu Lou1, Rui Bao, Cong Zhao Zhou, Yuxing Chen.   

Abstract

Human phosducin-like protein 2 (hPDCL2) has been identified as belonging to subgroup II of the phosducin (Pdc) family. The members of this family share an N-terminal helix domain and a C-terminal thioredoxin-fold (Trx-fold) domain. The X-ray crystal structure of the Trx-fold domain of hPDCL2 was solved at 2.70 A resolution and resembled the Trx-fold domain of rat phosducin. Comparative structural analysis revealed the structural basis of their putative functional divergence.

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Year:  2009        PMID： 19193988      PMCID： PMC2635858          DOI： 10.1107/S1744309108037342

Source DB:  PubMed          Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun        ISSN： 1744-3091


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