Literature DB >> 19193984

Mitochondria and aging: innocent bystanders or guilty parties?

K Tońska1, A Sołyga, E Bartnik.   

Abstract

There are many theories of aging and a number of them encompass the role of mitochondria in this process. Mitochondrial DNA mutations and deletions have been shown to accumulate in many tissues in mammals during aging. However, there is little evidence that these mutations could affect the functioning of aging tissues.

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Year:  2009        PMID: 19193984     DOI: 10.1007/BF03195653

Source DB:  PubMed          Journal:  J Appl Genet        ISSN: 1234-1983            Impact factor:   3.240


  56 in total

1.  Aging: a theory based on free radical and radiation chemistry.

Authors:  D HARMAN
Journal:  J Gerontol       Date:  1956-07

Review 2.  Mitochondrial DNA involvement in human longevity.

Authors:  Aurelia Santoro; Stefano Salvioli; Nicola Raule; Miriam Capri; Federica Sevini; Silvana Valensin; Daniela Monti; Dina Bellizzi; Giuseppe Passarino; Giuseppina Rose; Giovanna De Benedictis; Claudio Franceschi
Journal:  Biochim Biophys Acta       Date:  2006-06-07

Review 3.  'To repair or not to repair - no longer a question': repair of mitochondrial DNA shielding against age and cancer.

Authors:  Mark Berneburg; York Kamenisch; Jean Krutmann; Martin Röcken
Journal:  Exp Dermatol       Date:  2006-12       Impact factor: 3.960

4.  Quantitative effect of 4977 bp deletion of mitochondrial DNA on the susceptibility of human cells to UV-induced apoptosis.

Authors:  Chun-Yi Liu; Cheng-Feng Lee; Yau-Huei Wei
Journal:  Mitochondrion       Date:  2006-12-09       Impact factor: 4.160

Review 5.  Skin aging.

Authors:  Neira Puizina-Ivić
Journal:  Acta Dermatovenerol Alp Pannonica Adriat       Date:  2008-06

Review 6.  Molecular biology of aging.

Authors:  F B Johnson; D A Sinclair; L Guarente
Journal:  Cell       Date:  1999-01-22       Impact factor: 41.582

7.  Mitochondrial DNA inherited variants are associated with successful aging and longevity in humans.

Authors:  G De Benedictis; G Rose; G Carrieri; M De Luca; E Falcone; G Passarino; M Bonafe; D Monti; G Baggio; S Bertolini; D Mari; R Mattace; C Franceschi
Journal:  FASEB J       Date:  1999-09       Impact factor: 5.191

8.  Does premature aging of the mtDNA mutator mouse prove that mtDNA mutations are involved in natural aging?

Authors:  Konstantin Khrapko; Yevgenya Kraytsberg; Aubrey D N J de Grey; Jan Vijg; Eric A Schon
Journal:  Aging Cell       Date:  2006-06       Impact factor: 9.304

9.  Spontaneous Kearns-Sayre/chronic external ophthalmoplegia plus syndrome associated with a mitochondrial DNA deletion: a slip-replication model and metabolic therapy.

Authors:  J M Shoffner; M T Lott; A S Voljavec; S A Soueidan; D A Costigan; D C Wallace
Journal:  Proc Natl Acad Sci U S A       Date:  1989-10       Impact factor: 11.205

10.  Cosegregation of novel mitochondrial 16S rRNA gene mutations with the age-associated T414G variant in human cybrids.

Authors:  Peter Seibel; Chiara Di Nunno; Christian Kukat; Ingo Schäfer; Roberto Del Bo; Andreina Bordoni; Giacomo P Comi; Astrid Schön; Ferdinando Capuano; Dominga Latorre; Gaetano Villani
Journal:  Nucleic Acids Res       Date:  2008-09-16       Impact factor: 16.971

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  6 in total

1.  Mitochondrial DNA deletions and differential mitochondrial DNA content in Rhesus monkeys: implications for aging.

Authors:  Peizhong Mao; Patience Gallagher; Samira Nedungadi; Maria Manczak; Ulziibat P Shirendeb; Steven G Kohama; Betsy Ferguson; Byung S Park; P Hemachandra Reddy
Journal:  Biochim Biophys Acta       Date:  2011-10-28

Review 2.  Mitochondrial base excision repair assays.

Authors:  Scott Maynard; Nadja C de Souza-Pinto; Morten Scheibye-Knudsen; Vilhelm A Bohr
Journal:  Methods       Date:  2010-02-25       Impact factor: 3.608

Review 3.  Mitochondrial pathways in sarcopenia of aging and disuse muscle atrophy.

Authors:  Riccardo Calvani; Anna-Maria Joseph; Peter J Adhihetty; Alfredo Miccheli; Maurizio Bossola; Christiaan Leeuwenburgh; Roberto Bernabei; Emanuele Marzetti
Journal:  Biol Chem       Date:  2013-03       Impact factor: 3.915

4.  Mitochondrial Dysfunction and Oxidative Stress in Asthma: Implications for Mitochondria-Targeted Antioxidant Therapeutics.

Authors:  P Hemachandra Reddy
Journal:  Pharmaceuticals (Basel)       Date:  2011-02-25

5.  Accumulation of exogenous amyloid-beta peptide in hippocampal mitochondria causes their dysfunction: a protective role for melatonin.

Authors:  Sergio Rosales-Corral; Dario Acuna-Castroviejo; Dun Xian Tan; Gabriela López-Armas; José Cruz-Ramos; Rubén Munoz; Valery G Melnikov; Lucien C Manchester; Russel J Reiter
Journal:  Oxid Med Cell Longev       Date:  2012-05-13       Impact factor: 6.543

6.  Mitochondrial-Nuclear Interactions Mediate Sex-Specific Transcriptional Profiles in Drosophila.

Authors:  Jim A Mossman; Jennifer G Tross; Nan Li; Zhijin Wu; David M Rand
Journal:  Genetics       Date:  2016-08-24       Impact factor: 4.562

  6 in total

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