Literature DB >> 19192670

Giant cell tumor of the sternum: a case report and review of the literature.

Hiroyuki Futani1, Yasuaki Okumura, Yuko Fukuda, Satoru Fukunaga, Seiki Hasegawa, Shinichi Yoshiya.   

Abstract

Giant cell tumor (GCT) is a relatively common and locally aggressive benign bone tumor. The sternum is a rare location. To date, only four cases have been reported with detailed information. Here, we present a case with sternal GCT and discuss the clinical manifestation and treatment, in addition to reviewing the literature. A 53-year-old female noted pain in the sternum after a trauma. Radiographic findings revealed an expanding osteolytic lesion in the body of the sternum. Extended curettage of the tumor was performed followed by polymethylmethacrylate (PMMA) filing. No recurrence was found over a 7-year follow-up period. In conclusion, even though sternal benign tumors are rare, GCT should be considered as one of the differential diagnoses in a patient presenting with a sternal lesion in the 5th or 6th decade of life. The initial treatment should be extended curettage followed by filling with PMMA.

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Year:  2008        PMID: 19192670

Source DB:  PubMed          Journal:  Anticancer Res        ISSN: 0250-7005            Impact factor:   2.480


  5 in total

Review 1.  Modern interpretation of giant cell tumor of bone: predominantly osteoclastogenic stromal tumor.

Authors:  Yuhree Kim; Saqib Nizami; Hana Goto; Francis Y Lee
Journal:  Clin Orthop Surg       Date:  2012-05-17

2.  Clinical and cytogenetic aspects of giant cell tumor of the sternum.

Authors:  Edgard Eduard Engel; Marcello Henrique Nogueira-Barbosa; Maurício Eiji de Almeida Santos Yamashita; Federico Enrique Garcia Cipriano; Elvis Terci Valera; Maria Sol Brassesco
Journal:  Clinics (Sao Paulo)       Date:  2011       Impact factor: 2.365

Review 3.  Giant cell tumour of bone: new treatments in development.

Authors:  A López-Pousa; J Martín Broto; T Garrido; J Vázquez
Journal:  Clin Transl Oncol       Date:  2015-01-24       Impact factor: 3.405

4.  Surgical treatment of tumours of the sternum - 10 years' experience.

Authors:  Katarzyna Kozak; Mariusz P Łochowski; Adam Białas; Michał Rusinek; Józef Kozak
Journal:  Kardiochir Torakochirurgia Pol       Date:  2016-09-30

Review 5.  Primary malignant giant cell tumor of the sternum.

Authors:  Mohammed Imaduddin; Pavithra Ayyanar; Mahesh Sultania; Dillip Muduly; Mukund Namdev Sable; Suprava Naik; Sambit Mohanty; Madhabananda Kar
Journal:  Autops Case Rep       Date:  2021-05-25
  5 in total

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