D Cvejic1, T A Steinberg, M S Kent, A Fischer. 1. Section of Neurology, Clinic of Small Animal Medicine, Department of Veterinary Clinical Sciences, Ludwig Maximilian University, Munich, Germany.
Abstract
BACKGROUND: Congenital sensorineural deafness has been reported frequently in experimental mixed-breed white cats but there is a paucity of data on occurrence of deafness in client-owned pure-breed white cats. OBJECTIVE: To describe hearing status in client-owned pure-breed white cats. ANIMALS: Eighty-four pure-breed client-owned cats with white coat color of 10 registered breeds presented for routine hearing evaluation before breeding (1995-2008). METHODS: Hearing was assessed by click-evoked brainstem auditory evoked response. RESULTS: Overall deafness prevalence was 20.2%; 9 cats (10.7%) were bilaterally deaf and 8 cats (9.5%) were unilaterally deaf. There was no association between sex and deafness status (P= .85). Deafness status was associated with iris color (P= .04). CONCLUSIONS AND CLINICAL IMPORTANCE: Congenital sensorineural deafness frequently occurs in pure-breed cats with white coat color. Unilateral sensorineural deafness was as common as bilateral deafness.
BACKGROUND:Congenital sensorineural deafness has been reported frequently in experimental mixed-breed white cats but there is a paucity of data on occurrence of deafness in client-owned pure-breed white cats. OBJECTIVE: To describe hearing status in client-owned pure-breed white cats. ANIMALS: Eighty-four pure-breed client-owned cats with white coat color of 10 registered breeds presented for routine hearing evaluation before breeding (1995-2008). METHODS: Hearing was assessed by click-evoked brainstem auditory evoked response. RESULTS: Overall deafness prevalence was 20.2%; 9 cats (10.7%) were bilaterally deaf and 8 cats (9.5%) were unilaterally deaf. There was no association between sex and deafness status (P= .85). Deafness status was associated with iris color (P= .04). CONCLUSIONS AND CLINICAL IMPORTANCE: Congenital sensorineural deafness frequently occurs in pure-breed cats with white coat color. Unilateral sensorineural deafness was as common as bilateral deafness.
Authors: Sophia Grotz; Jessica Schäfer; Uwe Wolfrum; Nikolai Klymiuk; Kirsten A Wunderlich; Zdenka Ellederova; Hannah Auch; Andrea Bähr; Petra Runa-Vochozkova; Janet Fadl; Vanessa Arnold; Taras Ardan; Miroslav Veith; Gianluca Santamaria; Georg Dhom; Wolfgang Hitzl; Barbara Kessler; Christian Eckardt; Joshua Klein; Anna Brymova; Joshua Linnert; Mayuko Kurome; Valeri Zakharchenko; Andrea Fischer; Andreas Blutke; Anna Döring; Stepanka Suchankova; Jiri Popelar; Eduardo Rodríguez-Bocanegra; Julia Dlugaiczyk; Hans Straka; Helen May-Simera; Weiwei Wang; Karl-Ludwig Laugwitz; Luk H Vandenberghe; Eckhard Wolf; Kerstin Nagel-Wolfrum; Tobias Peters; Jan Motlik; M Dominik Fischer Journal: EMBO Mol Med Date: 2022-03-07 Impact factor: 12.137