Literature DB >> 1919015

Live attenuated Salmonella vaccines and their potential as oral combined vaccines carrying heterologous antigens.

C E Hormaeche1.   

Abstract

Live attenuated salmonellae are protective, and are candidate vaccines against invasive salmonella infections in man and animals. Different attenuating mutations have been described, and more than one can be incorporated in a vaccine for added safety. Combined salmonella vaccines express target carbohydrate and protein antigens or epitopes from viruses, bacteria and eukaryotic parasites, either within or on the surface of the cell, as capsules, fimbriae, or in the flagellin. Humoral, secretory and cellular responses to the recombinant antigens has been demonstrated. Experimental protection against diseases including streptococcal infection, tetanus, influenza and malaria has been obtained.

Entities:  

Mesh：

Substances：

Year:  1991        PMID： 1919015     DOI： 10.1016/0022-1759(91)90298-t

Source DB:  PubMed          Journal:  J Immunol Methods        ISSN： 0022-1759            Impact factor:   2.303


  8 in total

Review 1.  Bacteria as vectors for gene therapy of cancer.

Authors:  Chwanrow K Baban; Michelle Cronin; Deirdre O'Hanlon; Gerald C O'Sullivan; Mark Tangney
Journal:  Bioeng Bugs       Date:  2010 Nov-Dec

2.  Safety and immunogenicity of Salmonella typhimurium expressing C-terminal truncated human IL-2 in a murine model.

Authors:  Brent Sorenson; Kaysie Banton; Lance Augustin; Sean Barnett; Karen McCulloch; Joshua Dorn; Natalie Frykman; Arnold Leonard; Daniel Saltzman
Journal:  Biologics       Date:  2010-03-24

3.  DNA-Salmonella enterica serovar Typhimurium primer-booster vaccination biases towards T helper 1 responses and enhances protection against Leishmania major infection in mice.

Authors:  Uta G Lange; Pietro Mastroeni; Jenefer M Blackwell; Carmel B Stober
Journal:  Infect Immun       Date:  2004-08       Impact factor: 3.441

4.  Isolation and characterization of a cloned Porphyromonas gingivalis hemagglutinin from an avirulent strain of Salmonella typhimurium.

Authors:  D M Dusek; A Progulske-Fox; J Whitlock; T A Brown
Journal:  Infect Immun       Date:  1993-03       Impact factor: 3.441

5.  Listeria monocytogenes p60 supports host cell invasion by and in vivo survival of attenuated Salmonella typhimurium.

Authors:  J Hess; I Gentschev; G Szalay; C Ladel; A Bubert; W Goebel; S H Kaufmann
Journal:  Infect Immun       Date:  1995-05       Impact factor: 3.441

6.  Genetic control of immune response to recombinant antigens carried by an attenuated Salmonella typhimurium vaccine strain: Nramp1 influences T-helper subset responses and protection against leishmanial challenge.

Authors:  S S Soo; B Villarreal-Ramos; C M Anjam Khan; C E Hormaeche; J M Blackwell
Journal:  Infect Immun       Date:  1998-05       Impact factor: 3.441

7.  Refinement of a Live Attenuated Salmonella enterica Serovar Newport Vaccine with Improved Safety.

Authors:  Shamima Nasrin; Fabien J Fuche; Khandra T Sears; Jennifer A Jones; Myron M Levine; Raphael Simon; Sharon M Tennant
Journal:  Vaccines (Basel)       Date:  2021-01-16

Review 8.  Live vaccination tactics: possible approaches for controlling visceral leishmaniasis.

Authors:  Noushin Saljoughian; Tahareh Taheri; Sima Rafati
Journal:  Front Immunol       Date:  2014-03-31       Impact factor: 7.561
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.