Literature DB >> 19188966

A strategy for quantitative spectral imaging of tissue absorption and scattering using light emitting diodes and photodiodes.

Justin Y Lo1, Bing Yu, Henry L Fu, Janelle E Bender, Gregory M Palmer, Thomas F Kuech, Nirmala Ramanujam.   

Abstract

A diffuse reflectance spectroscopy system was modified as a step towards miniaturization and spectral imaging of tissue absorption and scattering. The modified system uses a tunable source and an optical fiber for illumination and a photodiode in contact with tissue for detection. Compared to the previous system, it is smaller, less costly, and has comparable performance in extracting optical properties in tissue phantoms. Wavelength reduction simulations show the feasibility of replacing the source with LEDs to further decrease system size and cost. Simulated crosstalk analysis indicates that this evolving system can be multiplexed for spectral imaging in the future.

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Year:  2009        PMID： 19188966     DOI： 10.1364/oe.17.001372

Source DB:  PubMed          Journal:  Opt Express        ISSN： 1094-4087            Impact factor:   3.894


  10 in total

1.  Design and fabrication of SiO2/TiO2 and MgO/TiO2 based high selective optical filters for diffuse reflectance and fluorescence signals extraction.

Authors:  S Pimenta; S Cardoso; A Miranda; P De Beule; E M S Castanheira; G Minas
Journal:  Biomed Opt Express       Date:  2015-07-29       Impact factor: 3.732

2.  Agarose-based Tissue Mimicking Optical Phantoms for Diffuse Reflectance Spectroscopy.

Authors:  Afrina Mustari; Izumi Nishidate; Md Abdul Wares; Takaaki Maeda; Satoko Kawauchi; Shunichi Sato; Manabu Sato; Yoshihisa Aizu
Journal:  J Vis Exp       Date:  2018-08-22       Impact factor: 1.355

3.  Optical assessment of tumor resection margins in the breast.

Authors:  J Quincy Brown; Torre M Bydlon; Lisa M Richards; Bing Yu; Stephanie A Kennedy; Joseph Geradts; Lee G Wilke; Marlee Junker; Jennifer Gallagher; William Barry; Nimmi Ramanujam
Journal:  IEEE J Sel Top Quantum Electron       Date:  2010-03-01       Impact factor: 4.544

4.  First-in-human pilot study of a spatial frequency domain oxygenation imaging system.

Authors:  Sylvain Gioux; Amaan Mazhar; Bernard T Lee; Samuel J Lin; Adam M Tobias; David J Cuccia; Alan Stockdale; Rafiou Oketokoun; Yoshitomo Ashitate; Edward Kelly; Maxwell Weinmann; Nicholas J Durr; Lorissa A Moffitt; Anthony J Durkin; Bruce J Tromberg; John V Frangioni
Journal:  J Biomed Opt       Date:  2011-08       Impact factor: 3.170

5.  Spatially resolved diffuse reflectance spectroscopy endoscopic sensing with custom Si photodetectors.

Authors:  Ben Lariviere; Katherine S Garman; N Lynn Ferguson; Deborah A Fisher; Nan M Jokerst
Journal:  Biomed Opt Express       Date:  2018-02-15       Impact factor: 3.732

6.  Diffuse reflectance spectroscopy of human liver tumor specimens - towards a tissue differentiating optical biopsy needle using light emitting diodes.

Authors:  Alina Keller; Piotr Bialecki; Torsten Johannes Wilhelm; Marcus Klaus Vetter
Journal:  Biomed Opt Express       Date:  2018-02-08       Impact factor: 3.732

7.  Narrow-band pass filter array for integrated opto-electronic spectroscopy detectors to assess esophageal tissue.

Authors:  Débora S Ferreira; Jelena Mirkovic; Reinoud F Wolffenbuttel; José H Correia; Michael S Feld; Graça Minas
Journal:  Biomed Opt Express       Date:  2011-05-25       Impact factor: 3.732

8.  Optical microsystem for analysis of diffuse reflectance and fluorescence signals applied to early gastrointestinal cancer detection.

Authors:  Sara Pimenta; Elisabete M S Castanheira; Graça Minas
Journal:  Sensors (Basel)       Date:  2015-01-30       Impact factor: 3.576

9.  A diffuse reflectance spectral imaging system for tumor margin assessment using custom annular photodiode arrays.

Authors:  Sulochana Dhar; Justin Y Lo; Gregory M Palmer; Martin A Brooke; Brandon S Nichols; Bing Yu; Nirmala Ramanujam; Nan M Jokerst
Journal:  Biomed Opt Express       Date:  2012-11-08       Impact factor: 3.732

10.  Wavelength optimization for quantitative spectral imaging of breast tumor margins.

Authors:  Justin Y Lo; J Quincy Brown; Sulochana Dhar; Bing Yu; Gregory M Palmer; Nan M Jokerst; Nirmala Ramanujam
Journal:  PLoS One       Date:  2013-04-16       Impact factor: 3.240
  10 in total

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