| Literature DB >> 19188066 |
Alexander S Kiselyov1, Marina Semenova, Victor V Semenov.
Abstract
Derivatives of (1,2,3-triazol-4-yl)benzenamines are described as potent and ATP-competitive inhibitors of vascular endothelial growth factor receptors I and II (VEGFR-1/2). A number of compounds exhibited VEGFR-2 and VEGFR-1 inhibitory activity comparable to that of Vatalanib in both HTRF enzymatic and cellular assays.Entities:
Mesh：
Substances：
Year: 2009 PMID： 19188066 DOI： 10.1016/j.bmcl.2009.01.046
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823