| Literature DB >> 19187768 |
Irfan J Lodhi1, Clay F Semenkovich.
Abstract
Mitochondrial uncoupling protein 1 (UCP1) is a key regulator of adaptive thermogenesis and energy expenditure. Mice lacking UCP1 are cold sensitive, but surprisingly not obese at room temperature. In this issue of Cell Metabolism, Feldmann et al. (2009) unmask an obesogenic phenotype by simply maintaining these mice at thermoneutrality.Entities:
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Year: 2009 PMID: 19187768 DOI: 10.1016/j.cmet.2009.01.004
Source DB: PubMed Journal: Cell Metab ISSN: 1550-4131 Impact factor: 27.287