OBJECTIVE: To identify the origin of calcified tissue in endometrial ossification. DESIGN: DNA analyses from the ossified tissue and from the woman were studied to compare both genotypes. SETTING: University and general hospitals. PATIENT(S): A 27-year-old infertile woman diagnosed of osseous metaplasia of the endometrium. INTERVENTION(S): Hysteroscopic resection of the endometrial osseous metaplasia for DNA analysis. MAIN OUTCOME MEASURE(S): DNA comparison between the patient and the osseous tissue extracted from the uterus. RESULT(S): All markers produced the same allele length for both blood and endometrial biopsy (including bones), thus confirming the same genetic origin. CONCLUSION(S): Endometrial ossification is derived from the patient, resulting in a true osseous metaplasia.
OBJECTIVE: To identify the origin of calcified tissue in endometrial ossification. DESIGN: DNA analyses from the ossified tissue and from the woman were studied to compare both genotypes. SETTING: University and general hospitals. PATIENT(S): A 27-year-old infertilewoman diagnosed of osseous metaplasia of the endometrium. INTERVENTION(S): Hysteroscopic resection of the endometrial osseous metaplasia for DNA analysis. MAIN OUTCOME MEASURE(S): DNA comparison between the patient and the osseous tissue extracted from the uterus. RESULT(S): All markers produced the same allele length for both blood and endometrial biopsy (including bones), thus confirming the same genetic origin. CONCLUSION(S): Endometrial ossification is derived from the patient, resulting in a true osseous metaplasia.
Authors: Luiz Felipe Alves Guerra; Laís Bastos Pessanha; Gabriel Antonio de Oliveira; Adriana Maria Fonseca de Melo; Flavia Silva Braga; Rodrigo Stênio Moll de Souza Journal: Radiol Bras Date: 2016 Jan-Feb