| Literature DB >> 19185599 |
Pedro Carnieli1, Juliana Galera Castilho, Willian de Oliveira Fahl, Nazle Mendonça Collaço Véras, Maria Luiza Carrieri, Ivanete Kotait.
Abstract
Thirty-eight samples of Rabies Virus isolated from dogs and crab-eating foxes (Cerdocyon thous) in Northeastern Brazil were characterized genetically by analyzing the G gene and the psi region. The results show that there are two groups of Rabies Virus lineages circulating among domestic and wild animals in the region. The topologies of the phylogenetic trees of the G gene and psi region are similar and reveal the existence of geographic groups. The genetic diversity of the lineages isolated from wild animals (wild group) was approximately twice that of the lineages isolated from domestic animals (domestic group), and the genetic distance between the two groups was 9.93%. Polymorphism analysis revealed specific intra- and inter-group molecular signatures for both the G gene and psi region. Together with the analysis of the N gene undertaken previously, the results of this study confirm the existence of a Rabies Virus phylogroup in Northeastern Brazil (NB) circulating in the C. thous population, making this species a rabies biotype in the region.Entities:
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Year: 2009 PMID： 19185599 DOI： 10.1016/j.virusres.2008.12.015
Source DB: PubMed Journal: Virus Res ISSN： 0168-1702 Impact factor: 3.303