Literature DB >> 19184604

Metastatic uterine leiomyosarcoma presenting as a breast lump.

S Sibartie1, J O Larkin, G Lee, J Fitzgibbon, S O'Reilly, D Richardson.   

Abstract

BACKGROUND: It is uncommon to encounter a breast metastasis from an extramammary malignancy and even rarer from a uterine leiomyosarcoma. AIMS: We describe the third case report in the medical literature of a breast metastasis from a uterine leiomyosarcoma.
METHODS: We report the management of a 56-year-old patient who presented with a breast lump 3 years after hysterectomy for a fibroid uterus. We conducted a literature review of breast leiomyosarcomas.
RESULTS: The excision of the breast mass revealed a low-grade leiomyosarcoma. Radiographic examinations demonstrated metastases to the lung, liver, pelvis and bone. Retrospective pathology review of her uterus identified a small focus of leiomyosarcoma. She received chemotherapy and palliative radiotherapy but passed away within few months.
CONCLUSION: Metastasis to the breast from a non-breast primary is generally a sign of disseminated disease and; thus, a poor prognostic indicator.

Entities:  

Mesh:

Year:  2009        PMID: 19184604     DOI: 10.1007/s11845-009-0286-8

Source DB:  PubMed          Journal:  Ir J Med Sci        ISSN: 0021-1265            Impact factor:   1.568


  6 in total

1.  Activity of trabectedin (ET-743, Yondelis) in metastatic uterine leiomyosarcoma.

Authors:  Devansu Tewari; Bahman Saffari; Carol Cowan; Anita C Wallick; M Zach Koontz; Bradley J Monk
Journal:  Gynecol Oncol       Date:  2006-06-23       Impact factor: 5.482

2.  Metastatic disease to the breast: clinical, pathologic, and radiographic features.

Authors:  B D Toombs; L Kalisher
Journal:  AJR Am J Roentgenol       Date:  1977-10       Impact factor: 3.959

3.  Breast metastasis from uterine leiomyosarcoma: a case report.

Authors:  Cheng-Hung Lin; Chun-Nan Yeh; Miin-Fu Chen
Journal:  Arch Gynecol Obstet       Date:  2002-06-06       Impact factor: 2.344

4.  Metastases to the breast.

Authors:  E S McCrea; C Johnston; P J Haney
Journal:  AJR Am J Roentgenol       Date:  1983-10       Impact factor: 3.959

5.  Diagnosis and natural history of extramammary tumors metastatic to the breast.

Authors:  B Chaignaud; T J Hall; C Powers; C Subramony; C E Scott-Conner
Journal:  J Am Coll Surg       Date:  1994-07       Impact factor: 6.113

6.  Ultrasound-guided fine needle aspiration cytodiagnosis of leiomyosarcoma metastatic to the breast. A case report.

Authors:  Merle N Madigan; Peter J Dempsey; Savitri Krishnamurthy
Journal:  Acta Cytol       Date:  2003 Sep-Oct       Impact factor: 2.319

  6 in total
  5 in total

1.  Fluorodeoxyglucose positron emission tomography in leiomyosarcoma: imaging characteristics.

Authors:  Stephanie E W Punt; Janet F Eary; Janet O'Sullivan; Ernest U Conrad
Journal:  Nucl Med Commun       Date:  2009-07       Impact factor: 1.690

Review 2.  Isolated cutaneous metastasis of uterine leiomyosarcoma: case report and review of literature.

Authors:  Shane Corcoran; Aisling M Hogan; Tamas Nemeth; Fadel Bennani; Francis J Sullivan; Waqar Khan; Kevin Barry
Journal:  Diagn Pathol       Date:  2012-07-18       Impact factor: 2.644

3.  Pulmonary metastasis from uterine leiomyosarcoma in a patient with limited cutaneous systemic scleroderma.

Authors:  Shinichiro Okauchi; Hiroko Watanabe; Tomohiro Tamura; Norio Takayashiki; Kesato Iguchi; Hiroaki Satoh; Taiki Sato; Akiko Sakata; Masayuki Noguchi
Journal:  J Gen Fam Med       Date:  2017-05-08

4.  Uterine leiomyosarcoma manifesting as a tricuspid valve mass.

Authors:  Creticus P Marak; Ana M Ponea; Narendrakumar Alappan; Shagufta Shaheen; Achuta K Guddati
Journal:  Case Rep Oncol       Date:  2013-02-28

5.  Lung Metastasis after an Eighteen-Years-Long Disease-Free Period since Uterine Leiomyosarcoma Diagnosis.

Authors:  M Guazzaroni; D Tosti; M Rascioni; M Mataloni; D Citraro; G Simonetti
Journal:  Case Rep Oncol Med       Date:  2014-03-12
  5 in total

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