Literature DB >> 19184073

Peritoneal tuberculosis with elevated serum Ca-125 level mimicking advanced stage ovarian cancer: a case report.

Orkun Tan1, Edward Luchansky, Stephen Rosenman, Tarah Pua, Masoud Azodi.   

Abstract

BACKGROUND: Tuberculosis is still a common problem in immigrant population with peritoneal tuberculosis as the most common presentation of extrapulmonary disease. CASE: A 36-year-old woman presented with abdominal distention, night sweats and weight loss. Physical examination and radiologic studies revealed ascites, omental caking and bilateral enlarged ovaries with an elevated serum Ca-125 of 353 U/mL. Acid-fast stain and culture were negative for Mycobacterium tuberculosis. Diagnostic laparoscopy and biopsy revealed multiple granulomas with epithelioid cells and caseification necrosis confirming tuberculosis. Treatment with anti-tuberculin drugs resulted in resolution of symptoms with a reduction in Ca-125 to normal.
CONCLUSION: Laparoscopic biopsy with frozen section evaluation would spare patients with peritoneal tuberculosis from unnecessary extensive surgery. Serum Ca-125 level may be useful in monitoring treatment response.

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Year:  2009        PMID: 19184073     DOI: 10.1007/s00404-009-0946-y

Source DB:  PubMed          Journal:  Arch Gynecol Obstet        ISSN: 0932-0067            Impact factor:   2.344


  2 in total

1.  [Pseudo-tumoral peritoneal tuberculosis mimicking ovarian cancer: an important differential diagnosis to consider].

Authors:  Mounir Moukit; Fatimazahra Ait El Fadel; Jaouad Kouach; Abdellah Babahabib; Mohammed Dehayni; Driss Moussaoui Rahali
Journal:  Pan Afr Med J       Date:  2016-11-25

2.  Clinical significance of serum CA-125 in Korean females with ascites.

Authors:  So Young Bae; Jun Haeng Lee; Jun Young Park; Da-min Kim; Byung-Hoon Min; Poong-Lyul Rhee; Jae J Kim
Journal:  Yonsei Med J       Date:  2013-09       Impact factor: 2.759

  2 in total

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