BACKGROUND: The timing of surgery for malignant sacrococcygeal teratoma is controversial. The long-term outcomes and complications of surgery for this rare tumour are presented. METHODS: All cases of malignant sacrococcygeal teratoma in the 20-year period 1987-2006 were identified and the case notes retrieved. The age at diagnosis, investigations, presentation, type of surgery, early complications, recurrence rates, long-term complications and outcomes were recorded. RESULTS: Twelve patients (three males, nine females) were identified. Mean age at presentation was 20.8 months (range: 12-39 months). All had the Carboplatin-Etoposide-Bleomycin chemotherapeutic protocol. The average time of follow-up was 10.6 years (range: 1-17 years). Ten patients had excision of their tumours following chemotherapy, whilst two patients had excision prior to chemotherapy. Two patients had recurrence of their tumours. There was one death (8%), which was due to disseminated metastasis. The other 11 children were all well at the last follow-up. CONCLUSION: Surgery for malignant sacrococcygeal teratoma is safe and has a low complication rate. The long-term outcomes are favourable with minimal side effects.
BACKGROUND: The timing of surgery for malignant sacrococcygeal teratoma is controversial. The long-term outcomes and complications of surgery for this rare tumour are presented. METHODS: All cases of malignant sacrococcygeal teratoma in the 20-year period 1987-2006 were identified and the case notes retrieved. The age at diagnosis, investigations, presentation, type of surgery, early complications, recurrence rates, long-term complications and outcomes were recorded. RESULTS: Twelve patients (three males, nine females) were identified. Mean age at presentation was 20.8 months (range: 12-39 months). All had the Carboplatin-Etoposide-Bleomycin chemotherapeutic protocol. The average time of follow-up was 10.6 years (range: 1-17 years). Ten patients had excision of their tumours following chemotherapy, whilst two patients had excision prior to chemotherapy. Two patients had recurrence of their tumours. There was one death (8%), which was due to disseminated metastasis. The other 11 children were all well at the last follow-up. CONCLUSION: Surgery for malignant sacrococcygeal teratoma is safe and has a low complication rate. The long-term outcomes are favourable with minimal side effects.
Authors: Antoine De Backer; Gerard C Madern; Friederike G A J Hakvoort-Cammel; Patrick Haentjens; J Wolter Oosterhuis; Frans W J Hazebroek Journal: J Pediatr Surg Date: 2006-01 Impact factor: 2.545
Authors: G Calaminus; D T Schneider; J P M Bökkerink; H Gadner; D Harms; R Willers; U Göbel Journal: J Clin Oncol Date: 2003-03-01 Impact factor: 44.544
Authors: D T Schneider; R Wessalowski; G Calaminus; H Pape; M Bamberg; J Engert; K Waag; H Gadner; U Göbel Journal: J Clin Oncol Date: 2001-04-01 Impact factor: 44.544
Authors: U Göbel; D T Schneider; G Calaminus; H Jürgens; H J Spaar; W Sternschulte; K Waag; D Harms Journal: J Clin Oncol Date: 2001-04-01 Impact factor: 44.544
Authors: Jillian R Mann; Elizabeth S Gray; Claire Thornton; Faro Raafat; Kathleen Robinson; Gary S Collins; Peter Gornall; Simon N Huddart; Juliet P Hale; Anthony Oakhill Journal: J Clin Oncol Date: 2008-06-09 Impact factor: 44.544