Literature DB >> 19183968

Fluorescence properties of selected benzo[c]phenantridine alkaloids and studies of their interaction with CT DNA.

Jana Urbanová1, Premysl Lubal, Iva Slaninová, Eva Táborská, Petr Táborský.   

Abstract

The spectral, especially fluorescence properties, of seven selected quaternary benzo[c]phenantridine alkaloids (sanguinarine, chelerythrine, chelirubine, sanguirubine, chelilutine, sanguilutine, and macarpine) were studied in presence and in absence of double-stranded DNA. This study has proved dramatic differences in fluorescence emission of all studied alkaloids in presence of calf thymus DNA in comparison to fluorescence of free alkaloids. The most remarkable are changes in emission spectra of macarpine, chelirubine, and sanguirubine. Association constants (logK) for interaction of all studied alkaloids with CT DNA were calculated.

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Year:  2009        PMID: 19183968     DOI: 10.1007/s00216-009-2601-7

Source DB:  PubMed          Journal:  Anal Bioanal Chem        ISSN: 1618-2642            Impact factor:   4.142


  9 in total

Review 1.  Biophysical aspects and biological implications of the interaction of benzophenanthridine alkaloids with DNA.

Authors:  Motilal Maiti; Gopinatha Suresh Kumar
Journal:  Biophys Rev       Date:  2009-08-25

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Journal:  Biophys Rev       Date:  2020-10-31

3.  Novel phenanthridine (PHE-4i) derivative inhibits carrageenan-induced rat hind paw oedema through suppression of hydrogen sulfide.

Authors:  Leema George; Tamizhselvi Ramasamy; Venkatraman Manickam; Sathiyanarayanan Kulathu Iyer; Vidya Radhakrishnan
Journal:  Inflammopharmacology       Date:  2016-07-05       Impact factor: 4.473

Review 4.  Rediscovery of Traditional Plant Medicine: An Underestimated Anticancer Drug of Chelerythrine.

Authors:  Nianzhi Chen; Yulin Qi; Xiao Ma; Xiaolin Xiao; Qingsong Liu; Ting Xia; Juyi Xiang; Jinhao Zeng; Jianyuan Tang
Journal:  Front Pharmacol       Date:  2022-06-01       Impact factor: 5.988

5.  Polymorphic nucleic Acid binding of bioactive isoquinoline alkaloids and their role in cancer.

Authors:  Motilal Maiti; Gopinatha Suresh Kumar
Journal:  J Nucleic Acids       Date:  2009-12-15

6.  Influence of Solvent Polarity and DNA-Binding on Spectral Properties of Quaternary Benzo[c]phenanthridine Alkaloids.

Authors:  Michal Rájecký; Kristýna Šebrlová; Filip Mravec; Petr Táborský
Journal:  PLoS One       Date:  2015-06-19       Impact factor: 3.240

7.  Seasonal variation of bioactive alkaloid contents in Macleaya microcarpa (Maxim.) Fedde.

Authors:  Kristýna Pěnčíková; Jana Urbanová; Pavel Musil; Eva Táborská; Jana Gregorová
Journal:  Molecules       Date:  2011-04-20       Impact factor: 4.411

8.  Fluorescence, Absorption, Chromatography and Structural Transformation of Chelerythrine and Ethoxychelerythrine in Protic Solvents: A Comparative Study.

Authors:  Jinjin Cao; Yanhui Zheng; Ting Liu; Jiamiao Liu; Jinze Liu; Jing Wang; Qirui Sun; Wenhong Li; Yongju Wei
Journal:  Molecules       Date:  2022-07-22       Impact factor: 4.927

9.  Understanding of black salve toxicity by multi-compound cytotoxicity assays.

Authors:  Andrew Croaker; Arie Davis; Anthony Carroll; Lei Liu; Stephen P Myers
Journal:  BMC Complement Med Ther       Date:  2022-09-20
  9 in total

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