Literature DB >> 19183219

The association between depression and epilepsy in a nationally representative sample.

Esme Fuller-Thomson1, Sarah Brennenstuhl.   

Abstract

PURPOSE: To determine the: (1) national prevalence of epilepsy and depression; (2) prevalence of depression among those with epilepsy; (3) odds ratio of depression among those with epilepsy compared to those without, controlling for demographic characteristics; (4) demographic correlates of depression among those with epilepsy and those without; and, (5) health services utilization of those with epilepsy and depression.
METHODS: The full sample of the nationally representative 2000/2001 Canadian Community Health Survey (n = 130,880) was used to determine prevalence of epilepsy and depression. A subsample of 781 individuals reporting an epilepsy diagnosis and with complete depression data was used to determine prevalence and correlates of depression, and health service utilization patterns. Correlates of depression among those without epilepsy (n = 126,104) were also determined. Chi-square analyses, t-tests, prevalence ratios, and a logistic regression were conducted.
RESULTS: Thirteen percent of those with epilepsy were depressed, in comparison to 7% of those without (p < 0.001). Epilepsy was associated with 43% higher odds of depression when adjusting for demographic factors. The odds of depression among individuals with epilepsy were higher for females, visible minorities, older individuals, and individuals experiencing food insecurity. Visible minority and older age appear to be unique risk factors for depression in those with epilepsy as compared to those without. Thirty-eight percent of depressed respondents with epilepsy had no consultations with a mental health professional in the previous year. DISCUSSION: Medical professionals need to regularly assess levels of depression in their patients with epilepsy. This research helps guide which risk groups should be targeted.

Entities:  

Mesh:

Year:  2008        PMID: 19183219     DOI: 10.1111/j.1528-1167.2008.01803.x

Source DB:  PubMed          Journal:  Epilepsia        ISSN: 0013-9580            Impact factor:   5.864


  18 in total

Review 1.  Current Concepts of Memory Disorder in Epilepsy: Edging Towards a Network Account.

Authors:  Genevieve Rayner; Chris Tailby
Journal:  Curr Neurol Neurosci Rep       Date:  2017-08       Impact factor: 5.081

Review 2.  Depression in epilepsy: a critical review from a clinical perspective.

Authors:  Christian Hoppe; Christian E Elger
Journal:  Nat Rev Neurol       Date:  2011-07-12       Impact factor: 42.937

3.  Mechanisms of memory impairment in epilepsy depend on age at disease onset.

Authors:  Genevieve Rayner; Graeme D Jackson; Sarah J Wilson
Journal:  Neurology       Date:  2016-09-16       Impact factor: 9.910

Review 4.  [Coexistent depressive and anxiety disorders in epilepsy and multiple sclerosis: a challenge to neuropsychiatric practice].

Authors:  Hans-Peter Kapfhammer
Journal:  Neuropsychiatr       Date:  2014-05-20

5.  Psychiatric care in epilepsy surgery: who needs it?

Authors:  Genevieve Rayner; Sarah J Wilson
Journal:  Epilepsy Curr       Date:  2012-03       Impact factor: 7.500

Review 6.  Antidepressant therapy in epilepsy: can treating the comorbidities affect the underlying disorder?

Authors:  L Cardamone; M R Salzberg; T J O'Brien; N C Jones
Journal:  Br J Pharmacol       Date:  2013-04       Impact factor: 8.739

7.  The Contribution of Cognitive Networks to Depression in Epilepsy.

Authors:  Genevieve Rayner
Journal:  Epilepsy Curr       Date:  2017 Mar-Apr       Impact factor: 7.500

Review 8.  Depressive syndromes in neurological disorders.

Authors:  Julian Hellmann-Regen; Dominique Piber; Kim Hinkelmann; Stefan M Gold; Christoph Heesen; Carsten Spitzer; Matthias Endres; Christian Otte
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  2013-11       Impact factor: 5.270

Review 9.  [Depression and neurological diseases].

Authors:  D Piber; K Hinkelmann; S M Gold; C Heesen; C Spitzer; M Endres; C Otte
Journal:  Nervenarzt       Date:  2012-11       Impact factor: 1.214

Review 10.  Depression in epilepsy: a systematic review and meta-analysis.

Authors:  Kirsten M Fiest; Jonathan Dykeman; Scott B Patten; Samuel Wiebe; Gilaad G Kaplan; Colleen J Maxwell; Andrew G M Bulloch; Nathalie Jette
Journal:  Neurology       Date:  2012-11-21       Impact factor: 9.910

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