Literature DB >> 19183048

Caryophyllenes from a fungal culture of Chrysosporium pilosum.

Shu-Wei Yang1, Tze-Ming Chan, Joseph Terracciano, Eric Boehm, Reena Patel, Guodong Chen, David Loebenberg, Mahesh Patel, Vincent Gullo, Birendra Pramanik, Min Chu.   

Abstract

Four new caryophyllene derivatives, Sch 725432 (1), Sch 601253 (2), Sch 601254 (3), and Sch 725434 (4), were isolated from the fungal fermentation broth of Chrysosporium pilosum by reversed-phase HPLC purification. The structure elucidation of trioxygenated caryophyllenes 1-4 was accomplished on the basis of spectroscopic data interpretation. Sch 725434 (4) possesses a dihydrofuran-3-one ring, forming a tricyclic ring skeleton, which represents an unprecedented ring skeleton for the caryophyllene-type of sesquiterpenes. Compounds 1-4 were evaluated for their antifungal activity.

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Year:  2009        PMID： 19183048     DOI： 10.1021/np8006414

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  3 in total

1.  Synthesis of dihydrofuran-3-one and 9,10-phenanthrenequinone hybrid molecules and biological evaluation against colon cancer cells as selective Akt kinase inhibitors.

Authors:  Jingjing Huang; Yufei Chen; Yinfeng Guo; Ming Bao; Kemiao Hong; Yuanqing Zhang; Wenhao Hu; Jinping Lei; Yongqiang Liu; Xinfang Xu
Journal:  Mol Divers       Date:  2022-06-25       Impact factor: 2.943

2.  Punctaporonins H-M: caryophyllene-type sesquiterpenoids from the sponge-associated fungus Hansfordia sinuosae.

Authors:  Zehong Wu; Dong Liu; Peter Proksch; Peng Guo; Wenhan Lin
Journal:  Mar Drugs       Date:  2014-06-30       Impact factor: 5.118

3.  Identification and characterization of compounds from Chrysosporium multifidum, a fungus with moderate antimicrobial activity isolated from Hermetia illucens gut microbiota.

Authors:  Yesenia Correa; Billy Cabanillas; Valérie Jullian; Daniela Álvarez; Denis Castillo; Cédric Dufloer; Beatriz Bustamante; Elisa Roncal; Edgar Neyra; Patricia Sheen; Michel Sauvain
Journal:  PLoS One       Date:  2019-12-20       Impact factor: 3.240
  3 in total

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