| Literature DB >> 19183005 |
Abstract
This paper is concerned with a novel algorithm to study networks of biological clocks. A new set of conditions is established that can be used to verify whether an existing network synchronizes or to give guidelines to construct a new synthetic network of biological oscillators that synchronize. The methodology uses the so-called contraction theory from dynamical system theory and Gershgorin disk theorem. The strategy is validated on two examples: a model of glycolisis in yeast cells and a synthetic network of Repressilators that synchronizes.Entities:
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Year: 2009 PMID: 19183005 DOI: 10.1089/cmb.2008.21TT
Source DB: PubMed Journal: J Comput Biol ISSN: 1066-5277 Impact factor: 1.479