Literature DB >> 19182702

Bifocals in Down Syndrome Study (BiDS): design and baseline visual function.

Krithika Nandakumar1, Susan J Leat.   

Abstract

PURPOSE: Among children and young people with Down syndrome (DS) there is a high prevalence of reduced accommodation. Prescribing bifocals for these patients has not become fully clinically accepted, although it would be anticipated to improve visual acuity (VA). The aim of this study is to investigate the impact of bifocal correction on VA, visual perceptual skills and early literacy development in children with DS who have reduced accommodation and who are provided with a bifocal correction. This paper describes the study design and the baseline optometric findings.
METHODS: We have chosen a longitudinal design with frequent measures of subtests of performance to control for progression with time. The main outcome measures are early literacy and visual perception skills. Secondary outcomes are VA and accommodative function. These are measured at baseline, the participant followed for 6 months when bifocals are prescribed if necessary, and the participants were followed for another 6 months with bifocals.
RESULTS: Fourteen participants with DS aged 8 to 19 years were enrolled. At baseline 79% required a change in their distance spectacle prescription. One hundred percent had reduced accommodation both before and after new single vision glasses were prescribed. None had an adverse reaction to 0.5 or 1% Cyclopentolate. All the subjects were able to perform either a distance or near crowded Patti-pics symbols test and 93% were able to perform both. There was a significant improvement of near VA with the new single vision spectacles (p = 0.015). The mean binocular distance VA was 0.362 +/- 0.17 logMAR whereas binocular near VA was 0.489 +/- 0.235.
CONCLUSION: This study confirms previous findings of a high prevalence of reduced accommodation and shows that near VA is reduced compared to distance VA. The present results indicate that all subjects might benefit from bifocals.

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Year:  2009        PMID: 19182702     DOI: 10.1097/OPX.0b013e318196cd93

Source DB:  PubMed          Journal:  Optom Vis Sci        ISSN: 1040-5488            Impact factor:   1.973


  5 in total

1.  Static and dynamic measurements of accommodation in individuals with down syndrome.

Authors:  Heather A Anderson; Ruth E Manny; Adrian Glasser; Karla K Stuebing
Journal:  Invest Ophthalmol Vis Sci       Date:  2011-01-05       Impact factor: 4.799

2.  Determining the relative contribution of retinal disparity and blur cues to ocular accommodation in Down syndrome.

Authors:  Lesley Doyle; Kathryn J Saunders; Julie-Anne Little
Journal:  Sci Rep       Date:  2017-01-10       Impact factor: 4.379

3.  Bifocals reduce strabismus in children with Down syndrome: Evidence from a randomized controlled trial.

Authors:  Christine de Weger; Nienke Boonstra; Jeroen Goossens
Journal:  Acta Ophthalmol       Date:  2019-07-17       Impact factor: 3.761

4.  Trying to see, failing to focus: near visual impairment in Down syndrome.

Authors:  Lesley Doyle; Kathryn J Saunders; Julie-Anne Little
Journal:  Sci Rep       Date:  2016-02-05       Impact factor: 4.379

5.  Effects of bifocals on visual acuity in children with Down syndrome: a randomized controlled trial.

Authors:  Christine de Weger; Nienke Boonstra; Jeroen Goossens
Journal:  Acta Ophthalmol       Date:  2018-10-27       Impact factor: 3.761

  5 in total

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