Literature DB >> 1918194

Why yeast?

D Botstein1.   

Abstract

Yeast is an apparently strange "model" for the human genome, but it works because of the high degree of conservation in evolution between the primitive eukaryote and mammals. Moreover, the genic concentration in yeast--with almost no noncoding introns--packs the entire yeast genome into 16 chromosomes with only 10% of the DNA of one human chromosome.

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Year:  1991        PMID: 1918194     DOI: 10.1080/21548331.1991.11705312

Source DB:  PubMed          Journal:  Hosp Pract (Off Ed)        ISSN: 8750-2836


  2 in total

1.  Structure-based systematic isolation of conditional-lethal mutations in the single yeast calmodulin gene.

Authors:  Y Ohya; D Botstein
Journal:  Genetics       Date:  1994-12       Impact factor: 4.562

Review 2.  Exploiting Post-mitotic Yeast Cultures to Model Neurodegeneration.

Authors:  Andrea Ruetenik; Antonio Barrientos
Journal:  Front Mol Neurosci       Date:  2018-11-02       Impact factor: 5.639

  2 in total

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