Literature DB >> 19181797

The Rv1712 Locus from Mycobacterium tuberculosis H37Rv codes for a functional CMP kinase that preferentially phosphorylates dCMP.

Caroline Thum1, Cristopher Z Schneider, Mario S Palma, Diógenes S Santos, Luiz A Basso.   

Abstract

The Mycobacterium tuberculosis cmk gene, predicted to encode a CMP kinase (CMK), was cloned and expressed, and its product was purified to homogeneity. Steady-state kinetics confirmed that M. tuberculosis CMK is a monomer that preferentially phosphorylates CMP and dCMP by a sequential mechanism. A plausible role for CMK is discussed.

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Year:  2009        PMID： 19181797      PMCID： PMC2668428          DOI： 10.1128/JB.01337-08

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  24 in total

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2.  Structure and function of cytidine monophosphate kinase from Yersinia pseudotuberculosis, essential for virulence but not for survival.

Authors:  Nicola J Walker; Elizabeth A Clark; Donna C Ford; Helen L Bullifent; Erin V McAlister; Melanie L Duffield; K Ravi Acharya; Petra C F Oyston
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  4 in total

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