Literature DB >> 19180969

[Effects of Panax notoginseng saponins on antioxidation and preventing DNA damage caused by hydroxyl radical].

Yun-Tao Gao1, Wen-Bin Zhang, Li-Rong Yang, Xue-Mei Wang, Yi-Lin Yang.   

Abstract

Scavening effects of panax notoginseng saponins on active oxygen species in the systems of Fenton reaction, autoxidation of pyrogallol and riboflavine photosensitization were investigated by the mean of spectrophotometry. The inhibition of panax notoginseg saponins on the damage of DNA chain induced by hydroxyl radical by panax notoginseng saponins was observed by the mean of gelose gel electrophoresi and thiobartital spectrophotometry. The results showed that panax notoginseng saponins could scaven * OH, O2*- efficiently and protect DNA chains from being damaged by hydroxyl radical.

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Year:  2008        PMID: 19180969

Source DB:  PubMed          Journal:  Zhong Yao Cai        ISSN: 1001-4454


  3 in total

1.  Panax notoginseng stimulates alkaline phosphatase activity, collagen synthesis, and mineralization in osteoblastic MC3T3-E1 cells.

Authors:  Zhe Ji; Yizhao Cheng; Puwei Yuan; Xiaoqian Dang; Xiong Guo; Weizhuo Wang
Journal:  In Vitro Cell Dev Biol Anim       Date:  2015-04-23       Impact factor: 2.416

2.  Rapid but mild genoprotective effect on lymphocytic DNA with Panax notoginseng extract supplementation.

Authors:  Yim Tong Szeto; Loretta Kit Yee Lee
Journal:  J Intercult Ethnopharmacol       Date:  2014-08-26

Review 3.  Classical Active Ingredients and Extracts of Chinese Herbal Medicines: Pharmacokinetics, Pharmacodynamics, and Molecular Mechanisms for Ischemic Stroke.

Authors:  Ting Zhu; Lei Wang; Yicheng Feng; Guibo Sun; Xiaobo Sun
Journal:  Oxid Med Cell Longev       Date:  2021-03-13       Impact factor: 6.543

  3 in total

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