OBJECTIVE: To investigate the chemical constituents from Loquat leaf (Eriobotrya japonica). METHODS: Compounds were isolated by a combination of silica gel and ODS column chromatographies and preparative TLC and HPLC, their structures were identified by chemical and spectral methods. RESULTS: Nine triterpenes were isolated and identified as methyl betuliate (I), oleanolic acid (II), ursolic acid (III), methyl maslinate (IV), methyl corosolate, (methyl 2alpha-3alpha-dihydroxyurs-12-en-28-oate, V), maslinic acid (VI), corosolic acid (VII), tormentic acid (VIII), euscaphic acid (IX) from loquat leaf. CONCLUSION: Compounds I and V are obtained from this plant and Eriobotrya genus for the first time.
OBJECTIVE: To investigate the chemical constituents from Loquat leaf (Eriobotrya japonica). METHODS: Compounds were isolated by a combination of silica gel and ODS column chromatographies and preparative TLC and HPLC, their structures were identified by chemical and spectral methods. RESULTS: Nine triterpenes were isolated and identified as methyl betuliate (I), oleanolic acid (II), ursolic acid (III), methyl maslinate (IV), methyl corosolate, (methyl 2alpha-3alpha-dihydroxyurs-12-en-28-oate, V), maslinic acid (VI), corosolic acid (VII), tormentic acid (VIII), euscaphic acid (IX) from loquat leaf. CONCLUSION: Compounds I and V are obtained from this plant and Eriobotrya genus for the first time.