Literature DB >> 19179975

Fournier's gangrene: historical survey, current status, and case description.

Ryszard Zaba1, Andrzej Grzybowski, Janusz Prokop, Zbigniew Zaba, Czesław Zaba.   

Abstract

BACKGROUND: The first-documented clinical picture of the disease was made by Fournier in 1883. Its epidemiology has changed and is much different from the original. It is infectious in its etiology, affecting mostly men between 50 and 60 years of age. Predisposing factors include diabetes, neoplasms, chronic glucocorticoid therapy, immune-compromise, chemo- and radiotherapy, immunosuppression, Crohn's disease, and alcohol abuse. High mortality results from the rapid progress of the disease, leading to quick development of septic shock and multi-organ failure. Most important in the treatment of Fournier's gangrene are surgical debridement of the wound, fascia incision and drainage of necrotic lesion, and intravenous antibiotic therapy. The typical picture of the disease might be hidden by concomitant disease. CASE REPORT: A case of Fournier's gangrene in an 81-year-old woman with concomitant neurologic complications, hypertension, cardiomyopathy, and chronic obstructed pulmonary disease is described. Three days after the suspected diagnosis, the decision was made to fully remove the necrotic tissue surgically. Despite all the efforts of the medical team, the patient died 14 days after being diagnosed with Fournier gangrene. The immediate cause of death was septic shock.
CONCLUSIONS: In the early stages of the disease, before necrotic lesions occur, a final diagnosis might be difficult. In the present case, death was caused by the patient's advanced age, simultaneously appearing symptoms, and late surgical intervention, but mostly by lung failure.

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Year:  2009        PMID: 19179975

Source DB:  PubMed          Journal:  Med Sci Monit        ISSN: 1234-1010


  2 in total

1.  Fournier gangrene presenting in a patient with undiagnosed rectal adenocarcinoma: a case report.

Authors:  Mohammd Kazem Moslemi; Mohammad Ali Sadighi Gilani; Ali Akbar Moslemi; Ali Arabshahi
Journal:  Cases J       Date:  2009-12-03

2.  Evidence for Infections by the Same Strain of Beta 2-toxigenic Clostridium perfringens Type A Acquired in One Hospital Ward.

Authors:  Dominika Salamon; Dorota Ochońska; Ilona Wojak; Ewa Mikołajczyk; Małgorzata Bulanda; Monika Brzychczy-Włoch
Journal:  Pol J Microbiol       Date:  2019-09-03
  2 in total

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