Literature DB >> 19179071

Synthesis of citrate-ciprofloxacin conjugates.

Siti R Md-Saleh1, Emily C Chilvers, Kevin G Kerr, Stephen J Milner, Anna M Snelling, Jan P Weber, Gavin H Thomas, Anne-Kathrin Duhme-Klair, Anne Routledge.   

Abstract

Two regioisomeric citrate-functionalized ciprofloxacin conjugates have been synthesized and their antimicrobial activities against a panel of clinically-relevant bacteria have been determined. Cellular uptake mechanisms were investigated using wild-type and ompF deletion strains of Escherichia coli K-12.

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Year:  2009        PMID: 19179071     DOI: 10.1016/j.bmcl.2009.01.007

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  6 in total

1.  Esterase-Catalyzed Siderophore Hydrolysis Activates an Enterobactin-Ciprofloxacin Conjugate and Confers Targeted Antibacterial Activity.

Authors:  Wilma Neumann; Martina Sassone-Corsi; Manuela Raffatellu; Elizabeth M Nolan
Journal:  J Am Chem Soc       Date:  2018-04-10       Impact factor: 15.419

Review 2.  Exploiting bacterial iron acquisition: siderophore conjugates.

Authors:  Cheng Ji; Raúl E Juárez-Hernández; Marvin J Miller
Journal:  Future Med Chem       Date:  2012-03       Impact factor: 3.808

3.  Evaluation of a reducible disulfide linker for siderophore-mediated delivery of antibiotics.

Authors:  Wilma Neumann; Elizabeth M Nolan
Journal:  J Biol Inorg Chem       Date:  2018-07-02       Impact factor: 3.358

4.  Platform to Discover Protease-Activated Antibiotics and Application to Siderophore-Antibiotic Conjugates.

Authors:  Jonathan H Boyce; Bobo Dang; Beatrice Ary; Quinn Edmondson; Charles S Craik; William F DeGrado; Ian B Seiple
Journal:  J Am Chem Soc       Date:  2020-12-10       Impact factor: 15.419

Review 5.  Modifications of quinolones and fluoroquinolones: hybrid compounds and dual-action molecules.

Authors:  Joanna Fedorowicz; Jarosław Sączewski
Journal:  Monatsh Chem       Date:  2018-06-07       Impact factor: 1.451

6.  Synthesis of ciprofloxacin-conjugated poly (L-lactic acid) polymer for nanofiber fabrication and antibacterial evaluation.

Authors:  Sharad P Parwe; Priti N Chaudhari; Kavita K Mohite; Balaji S Selukar; Smita S Nande; Baijayantimala Garnaik
Journal:  Int J Nanomedicine       Date:  2014-03-26
  6 in total

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