| Literature DB >> 19179019 |
B Kairis1, P Sauter, A Goffard, S Fronval, F Sane, D Hober.
Abstract
Most of enterovirus infections are benign and the rate of mortality is low in countries with temperate climates. But since the late 1990s, Enterovirus 71 (EV-71) has become much more aggressive in Asian countries, with the outcome of a neurogenic pulmonary oedema syndrome and it is responsible for huge epidemics. The virological diagnosis rely upon viral isolation and identification by sero-neutralization, and upon the detection of specific IgM by ELISA and viral RNA by RT-PCR. There is no specific treatment to fight this virus, but innovative strategies, especially based on interfering RNA, are under investigation.Entities:
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Year: 2009 PMID: 19179019 DOI: 10.1016/j.patbio.2008.06.001
Source DB: PubMed Journal: Pathol Biol (Paris) ISSN: 0369-8114