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Literature DB >> 19177635

Unprecedented hemiketal cembranolides with anti-inflammatory activity from the soft coral Lobophytum durum.

Shi-Yie Cheng¹, Zhi-Hong Wen, Shang-Kwei Wang, Shu-Fen Chiou, Chi-Hsin Hsu, Chang-Feng Dai, Michael Y Chiang, Chang-Yih Duh.

Abstract

Chemical investigations of the soft coral Lobophytum durum have led to the isolation of three unprecedented hemiketal cembranolides, durumhemiketalolides A-C (1-3). Full NMR spectroscopic assignments are provided for all isolated metabolites. The anti-inflammatory activities of 1-3 were evaluated in vitro.

Entities: Chemical

Mesh：

Substances：

Year: 2009 PMID： 19177635 DOI： 10.1021/np800686k

Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050

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Cited

18 in total

1. Diversified Polyketides With Anti-inflammatory Activities From Mangrove Endophytic Fungus Daldinia eschscholtzii KBJYZ-1.

Authors: Guisheng Wang; Zhenhua Yin; Senye Wang; Yilin Yuan; Yan Chen; Wenyi Kang
Journal: Front Microbiol Date: 2022-05-10 Impact factor: 6.064

2. Cembranoids with 3,14-ether linkage and a secocembrane with bistetrahydrofuran from the Dongsha Atoll soft coral Lobophytum sp.

Authors: Mohamed Elamir F Hegazy; Jui-Hsin Su; Ping-Jyun Sung; Jyh-Horng Sheu
Journal: Mar Drugs Date: 2011-07-12 Impact factor: 6.085

3. New cembranolides from the Dongsha Atoll soft coral Lobophytum durum.

Authors: Shi-Yie Cheng; Pei-Wen Chen; Hwa-Pyng Chen; Shang-Kwei Wang; Chang-Yih Duh
Journal: Mar Drugs Date: 2011-07-27 Impact factor: 6.085

4. Bioactive cembranoids from the dongsha atoll soft coral Sarcophyton crassocaule.

Authors: Wan-Yu Lin; Yi Lu; Jui-Hsin Su; Zhi-Hong Wen; Chang-Feng Dai; Yao-Haur Kuo; Jyh-Horng Sheu
Journal: Mar Drugs Date: 2011-06-09 Impact factor: 6.085

Review 5. Cnidarians as a source of new marine bioactive compounds--an overview of the last decade and future steps for bioprospecting.

Authors: Joana Rocha; Luisa Peixe; Newton C M Gomes; Ricardo Calado
Journal: Mar Drugs Date: 2011-10-10 Impact factor: 6.085

Unprecedented hemiketal cembranolides with anti-inflammatory activity from the soft coral Lobophytum durum.

1. Diversified Polyketides With Anti-inflammatory Activities From Mangrove Endophytic Fungus Daldinia eschscholtzii KBJYZ-1.

2. Cembranoids with 3,14-ether linkage and a secocembrane with bistetrahydrofuran from the Dongsha Atoll soft coral Lobophytum sp.

3. New cembranolides from the Dongsha Atoll soft coral Lobophytum durum.

4. Bioactive cembranoids from the dongsha atoll soft coral Sarcophyton crassocaule.

Review 5. Cnidarians as a source of new marine bioactive compounds--an overview of the last decade and future steps for bioprospecting.

6. New cytotoxic cembranolides from the soft coral Lobophytum michaelae.

7. Terpenoids from the octocorals Menella sp. (Plexauridae) and Lobophytum crassum (Alcyonacea).

8. Cembranoids from the Dongsha Atoll soft coral Lobophytum crassum.

9. Sarcocrassocolides M-O, bioactive cembranoids from the Dongsha Atoll soft coral Sarcophyton crassocaule.

10. Oxygenated Cembranoids from the Soft Coral Sinularia flexibilis.