Literature DB >> 19177251

Gadolinium enhancement of the lumbar roots in a case of ALS.

Nathan P Young1, Ruple S Laughlin, Eric J Sorenson.   

Abstract

We present a single case of clinically definite amyotrophic lateral sclerosis (ALS) associated with modest gadolinium enhancement of the lumbar nerve roots without thickening or nodularity and with CSF protein elevation (80 mg/dl). These findings should not exclude a clinical diagnosis of ALS and suggest that the enhancement of nerve roots and protein elevation were related to rapid neuronal degeneration, not inflammation.

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Year:  2010        PMID： 19177251     DOI： 10.3109/17482960802642161

Source DB:  PubMed          Journal:  Amyotroph Lateral Scler        ISSN： 1471-180X


  3 in total

1.  Magnetic resonance imaging abnormalities of peripheral nerve and muscle are common in amyotrophic lateral sclerosis and share features with multifocal motor neuropathy.

Authors:  Nathan P Staff; Kimberly K Amrami; Benjamin M Howe
Journal:  Muscle Nerve       Date:  2015-05-28       Impact factor: 3.217

2.  Clinical and Molecular Landscape of ALS Patients with SOD1 Mutations: Novel Pathogenic Variants and Novel Phenotypes. A Single ALS Center Study.

Authors:  Emilien Bernard; Antoine Pegat; Juliette Svahn; Françoise Bouhour; Pascal Leblanc; Stéphanie Millecamps; Stéphane Thobois; Claire Guissart; Serge Lumbroso; Kevin Mouzat
Journal:  Int J Mol Sci       Date:  2020-09-16       Impact factor: 5.923

3.  Breached Barriers: A Scoping Review of Blood-Central Nervous System Barrier Pathology in Amyotrophic Lateral Sclerosis.

Authors:  Ario Mirian; Alexander Moszczynski; Serena Soleimani; Isabelle Aubert; Lorne Zinman; Agessandro Abrahao
Journal:  Front Cell Neurosci       Date:  2022-03-31       Impact factor: 5.505
  3 in total

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