Literature DB >> 19177221

Heterologous expression systems for polyketide synthases.

Isao Fujii1.   

Abstract

Polyketide synthases are the main biochemical machinery for the production of a structurally diverse group of natural products, polyketides. Their heterologous expression enables overproduction of target compounds, generation of novel analogs, and provides a basic understanding of their reaction programs. This Highlight outlines the current state of heterologous expression of type I, type II, and type III polyketide synthases of microbial and plant origins.

Entities:  

Mesh：

Substances：

Year:  2008        PMID： 19177221     DOI： 10.1039/b817092b

Source DB:  PubMed          Journal:  Nat Prod Rep        ISSN： 0265-0568            Impact factor:   13.423


  8 in total

Review 1.  Highlights of marine invertebrate-derived biosynthetic products: their biomedical potential and possible production by microbial associants.

Authors:  Ocky K Radjasa; Yvette M Vaske; Gabriel Navarro; Hélène C Vervoort; Karen Tenney; Roger G Linington; Phillip Crews
Journal:  Bioorg Med Chem       Date:  2011-07-26       Impact factor: 3.641

Review 2.  New insights into the formation of fungal aromatic polyketides.

Authors:  Jason M Crawford; Craig A Townsend
Journal:  Nat Rev Microbiol       Date:  2010-12       Impact factor: 60.633

Review 3.  A sea of biosynthesis: marine natural products meet the molecular age.

Authors:  Amy L Lane; Bradley S Moore
Journal:  Nat Prod Rep       Date:  2010-12-17       Impact factor: 13.423

Review 4.  Prokaryotic gene clusters: a rich toolbox for synthetic biology.

Authors:  Michael Fischbach; Christopher A Voigt
Journal:  Biotechnol J       Date:  2010-12       Impact factor: 4.677

5.  Development of a cyanobacterial heterologous polyketide production platform.

Authors:  Julia Roulet; Arnaud Taton; James W Golden; Ana Arabolaza; Michael D Burkart; Hugo Gramajo
Journal:  Metab Eng       Date:  2018-07-21       Impact factor: 9.783

Review 6.  Pseudomonas putida-a versatile host for the production of natural products.

Authors:  Anita Loeschcke; Stephan Thies
Journal:  Appl Microbiol Biotechnol       Date:  2015-06-23       Impact factor: 4.813

7.  Biocatalytic synthesis of non-standard amino acids by a decarboxylative aldol reaction.

Authors:  Jonathan M Ellis; Meghan E Campbell; Prasanth Kumar; Eric P Geunes; Craig A Bingman; Andrew R Buller
Journal:  Nat Catal       Date:  2022-02-21

Review 8.  The Phylum Bryozoa: From Biology to Biomedical Potential.

Authors:  Maria Letizia Ciavatta; Florence Lefranc; Leandro M Vieira; Robert Kiss; Marianna Carbone; Willem A L van Otterlo; Nicole B Lopanik; Andrea Waeschenbach
Journal:  Mar Drugs       Date:  2020-04-09       Impact factor: 5.118
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.