Literature DB >> 19176464

Trial offers early test case for personalized medicine.

Ken Garber.   

Abstract

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Year:  2009        PMID: 19176464     DOI: 10.1093/jnci/djn506

Source DB:  PubMed          Journal:  J Natl Cancer Inst        ISSN: 0027-8874            Impact factor:   13.506


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  5 in total

1.  MEK1/2 inhibitor selumetinib (AZD6244) inhibits growth of ovarian clear cell carcinoma in a PEA-15-dependent manner in a mouse xenograft model.

Authors:  Chandra Bartholomeusz; Tetsuro Oishi; Hitomi Saso; Ugur Akar; Ping Liu; Kimie Kondo; Anna Kazansky; Savitri Krishnamurthy; Jangsoon Lee; Francisco J Esteva; Junzo Kigawa; Naoto T Ueno
Journal:  Mol Cancer Ther       Date:  2011-12-05       Impact factor: 6.261

2.  The role of EGFR monoclonal antibodies (MoABs) cetuximab/panitumab, and BRAF inhibitors in BRAF mutated colorectal cancer.

Authors:  Shan Muhammad; Zheng Jiang; Zheng Liu; Kavanjit Kaur; Xishan Wang
Journal:  J Gastrointest Oncol       Date:  2013-03

3.  Approaches to phase 1 clinical trial design focused on safety, efficiency, and selected patient populations: a report from the clinical trial design task force of the national cancer institute investigational drug steering committee.

Authors:  S Percy Ivy; Lillian L Siu; Elizabeth Garrett-Mayer; Larry Rubinstein
Journal:  Clin Cancer Res       Date:  2010-03-09       Impact factor: 12.531

Review 4.  Pharmacogenetics and stroke.

Authors:  James F Meschia
Journal:  Stroke       Date:  2009-09-17       Impact factor: 7.914

Review 5.  Extracellular signal-regulated kinases modulate DNA damage response - a contributing factor to using MEK inhibitors in cancer therapy.

Authors:  F Wei; J Yan; D Tang
Journal:  Curr Med Chem       Date:  2011       Impact factor: 4.530

  5 in total

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