| Literature DB >> 1917591 |
P J Romano1, M Bartholomew, P J Smith, F Kloszewski, J Stryker, J Houck, E S Vesell.
Abstract
The concept of genetic factors playing a role in the pathogenesis of lung cancer has gained increased attention. The present study was undertaken to reexamine the question of HLA antigen association with carcinoma of the lung. In a study of 90 patients, a significant association occurred between HLA-DR7 and resistance to lung cancer, after accounting for smoking status and sex. HLA class I antigens were also implicated. These results suggest that major histocompatibility complex loci affect carcinoma of the lung.Entities:
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Year: 1991 PMID： 1917591 DOI： 10.1016/0198-8859(91)90093-o
Source DB: PubMed Journal: Hum Immunol ISSN： 0198-8859 Impact factor: 2.850