Literature DB >> 1917564

Immunohistochemical distribution of MAM-3 and MAM-6 antigens in developing salivary glands of the human fetus.

S K Lee1, C Y Lim, J G Chi, K Yamada, M Mori, A Tsubura, S Morii, J Hilgers, M Govindarajan.   

Abstract

The immunohistochemical expression of MAM-3 and MAM-6 antigens was studied developing human fetal salivary gland removed at autopsy of 22 normal fetuses of varying maturity (10-40 weeks of gestation). The onset of functional maturation in the fetal gland was seen at 21 weeks of gestational maturity. The acini and ducts then underwent distinct alterations in antigen expression with growth and maturation until the late developmental stage (33-40 weeks of gestation) when they resemble the adult salivary gland. The role of maturing duct cells in histogenesis of salivary gland tumours is discussed.

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Year:  1991        PMID: 1917564     DOI: 10.1007/bf01042180

Source DB:  PubMed          Journal:  Histochem J        ISSN: 0018-2214


  12 in total

1.  Immunohistochemical expression of MAM-3 and MAM-6 antigens in salivary gland tumours.

Authors:  K Yamada; T Tanaka; M Mori; A Tsubura; S Morii; M Tsubone; C Ando; J Hilgers
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1989

2.  Monoclonal antibodies to epithelial sialomucins recognize epitopes at different cellular sites in adenolymphomas of the parotid gland.

Authors:  S Zotter; P C Hageman; A Lossnitzer; J van den Tweel; J Hilkens; W J Mooi; J Hilgers
Journal:  Int J Cancer Suppl       Date:  1988

3.  Expression of MAM-3 and MAM-6 antigens in endometrial and endocervical adenocarcinomas.

Authors:  A Tsubura; S Morii; J Hilkens; J Hilgers
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1985

4.  Immunohistochemical identification of epithelial membrane antigen in sweat gland tumors by the use of a monoclonal antibody.

Authors:  Y Noda; H Horike; Y Watanabe; M Mori; T Tsujimura
Journal:  Pathol Res Pract       Date:  1987-12       Impact factor: 3.250

5.  Epithelial markers for paraffin-embedded human tissues. Immunohistochemistry with monoclonal antibodies against milk fat globule antigens.

Authors:  S Zotter; A Lossnitzer; K D Kunze; M Müller; J Hilkens; J Hilgers; P Hageman
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1985

6.  Immunohistochemical demonstration of MAM-3 and MAM-6 antigens in normal human skin appendages and their tumors.

Authors:  A Tsubura; S Morii; S Ueda; M Sasaki; S Zotter; V Watzig; W Mooi; P Hageman; J Hilkens; J Van den Tweel
Journal:  Arch Dermatol Res       Date:  1987       Impact factor: 3.017

7.  Epithelial membrane antigen--a diagnostic discriminant in surgical pathology: immunohistochemical profile in epithelial, mesenchymal, and hematopoietic neoplasms using paraffin sections and monoclonal antibodies.

Authors:  G S Pinkus; P J Kurtin
Journal:  Hum Pathol       Date:  1985-09       Impact factor: 3.466

8.  Complexity of MAM-6, an epithelial sialomucin associated with carcinomas.

Authors:  J Hilkens; F Buijs; M Ligtenberg
Journal:  Cancer Res       Date:  1989-02-15       Impact factor: 12.701

9.  Epithelial membrane antigen as a marker of human salivary gland acinar and ductal cell function.

Authors:  Y Tatemoto; S Kumasa; Y Watanabe; M Mori
Journal:  Acta Histochem       Date:  1987       Impact factor: 2.479

10.  Monoclonal antibodies against human milk-fat globule membranes detecting differentiation antigens of the mammary gland and its tumors.

Authors:  J Hilkens; F Buijs; J Hilgers; P Hageman; J Calafat; A Sonnenberg; M van der Valk
Journal:  Int J Cancer       Date:  1984-08-15       Impact factor: 7.396

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